Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ECE1 | P42892 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TACR3 | P29371 | 3/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | KDM4B | O94953 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20586012 | 1.00 | RAB9A (0.38) | RAB9ANPC1ALDH1A1PKMKDM4E | |
| SCHEMBL20587746 | 1.00 | RAB9A (0.38) | RAB9ANPC1ALDH1A1PKMKDM4E | |
| SCHEMBL20586011 | 1.00 | RAB9A (0.38) | RAB9ANPC1ALDH1A1PKMKDM4E | |
| SCHEMBL29638840 | 0.81 | KDM4E (0.43) | KDM4EHTT | |
| SCHEMBL21137404 | 0.81 | KDM4E (0.43) | KDM4EHTT | |
| SCHEMBL22961287 | 0.73 | ALDH1A1 (0.45) | ALDH1A1PKMKDM4EGAAHTT | |
| SCHEMBL21137403 | 0.73 | ALDH1A1 (0.45) | ALDH1A1PKMKDM4EGAAHTT | |
| SCHEMBL16211689 | 0.72 | MAP3K12 (0.34) | MAP3K12 | |
| Trifluoroacetic Acid SCHEMBL20584909 | 0.71 | SSTR4 (0.38) | RAB9ANPC1KDM4EPOLBGAA | |
| Trifluoroacetic Acid SCHEMBL29638837 | 0.71 | SSTR4 (0.38) | RAB9ANPC1KDM4EPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352342-B2 | Pharmaceutical compounds | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-06-07 | — | — | US | disclosed |
| US-20210040067-A1 | PHARMACEUTICAL COMPOUNDS | NXERA PHARMA UK LIMITED (GB) | 2021-02-11 | — | — | US | disclosed |
| US-10752610-B2 | Pharmaceutical compounds | HEPTARES THERAPEUTICS LIMITED (GB) | 2020-08-25 | — | — | US | disclosed |
| US-20190276437-A1 | PHARMACEUTICAL COMPOUNDS | NXERA PHARMA UK LIMITED (GB) | 2019-09-12 | — | — | US | disclosed |
| US-10329278-B2 | Pharmaceutical compounds | HEPTARES THERAPEUTICS LIMITED (GB) | 2019-06-25 | — | — | US | disclosed |
| US-20180362507-A1 | PHARMACEUTICAL COMPOUNDS | NXERA PHARMA UK LIMITED (GB) | 2018-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040067-A1 | PHARMACEUTICAL COMPOUNDS | CHRM1, CHRM2, CHRM4 | RAB9A 1785/4885NPC1 1586/4885ALDH1A1 1597/4885 |
| US-11352342-B2 | Pharmaceutical compounds | CHRM1, CHRM2, CHRM4 | RAB9A 1785/4885NPC1 1586/4885ALDH1A1 1597/4885 |
| US-10329278-B2 | Pharmaceutical compounds | CHRM1, CHRM2, CHRM4 | RAB9A 1787/4885NPC1 1751/4885ALDH1A1 2039/4885 |
| US-20190276437-A1 | PHARMACEUTICAL COMPOUNDS | CHRM1, CHRM2, CHRM4 | RAB9A 1785/4885NPC1 1586/4885ALDH1A1 1597/4885 |
| US-20180362507-A1 | PHARMACEUTICAL COMPOUNDS | CHRM1, CHRM2, CHRM4 | RAB9A 1787/4885NPC1 1751/4885ALDH1A1 2039/4885 |
| US-10752610-B2 | Pharmaceutical compounds | CHRM1, CHRM2, CHRM4 | RAB9A 1785/4885NPC1 1586/4885ALDH1A1 1597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.