Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 10/20 | 0.45 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6905308 | 0.82 | KDM1A (0.59) | HTR2CHTR2BKDM1AKDM1BDRD3 | |
| SCHEMBL6901210 | 0.82 | KDM1A (0.59) | HTR2CHTR2BKDM1AKDM1BDRD3 | |
| SCHEMBL16586674 | 0.75 | KDM1A (0.47) | HTR2CHTR2BKDM1AKDM1BDRD2 | |
| SCHEMBL16586820 | 0.75 | KDM1A (0.47) | HTR2CHTR2BKDM1AKDM1BDRD2 | |
| SCHEMBL16586821 | 0.75 | KDM1A (0.47) | HTR2CHTR2BKDM1AKDM1BDRD2 | |
| SCHEMBL16586672 | 0.75 | KDM1A (0.47) | HTR2CHTR2BKDM1AKDM1BDRD2 | |
| SCHEMBL16585935 | 0.75 | KDM1A (0.47) | HTR2CHTR2BKDM1AKDM1BDRD2 | |
| SCHEMBL16585933 | 0.75 | KDM1A (0.47) | HTR2CHTR2BKDM1AKDM1BDRD2 | |
| Hydrochloric Acid SCHEMBL16587030 | 0.74 | KDM1A (0.46) | HTR2CHTR2BKDM1AKDM1BDRD2 | |
| Hydrochloric Acid SCHEMBL16585848 | 0.74 | KDM1A (0.46) | HTR2CHTR2BKDM1AKDM1BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160075653-A1 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | BAYER ANIMAL HEALTH GMBH (DE) | 2016-03-17 | — | — | US | disclosed |
| EP-2991487-A1 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | Bayer CropScience Aktiengesellschaft (DE) | 2016-03-09 | — | — | EP | disclosed |
| WO-2014177487-A9 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2015-12-23 | — | — | WO | disclosed |
| WO-2014177487-A1 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2014-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075653-A1 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | DNPH1, AADAC, NAAA | HTR2C 1208/4885HTR2B 2084/4885KDM1A 2080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.