Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanoate SCHEMBL17727869 | 1.00 | MAPK1 (0.59) | MAPK1HSD17B3GPR84PPARGPPARD | |
| Dodecanoate SCHEMBL29144802 | 0.92 | HSD17B3 (0.67) | HSD17B3GPR84PPARGPPARDPPARA | |
| Stearic Acid SCHEMBL6765873 | 0.88 | HSD17B3 (0.61) | HSD17B3GPR84PPARGPPARDPPARA | |
| Dodecanoate SCHEMBL6767044 | 0.88 | HSD17B3 (0.61) | HSD17B3GPR84PPARGPPARDPPARA | |
| Stearic Acid SCHEMBL9065925 | 0.87 | HSD17B3 (0.59) | HSD17B3GPR84PPARGPPARDPPARA | |
| Stearic Acid SCHEMBL10396577 | 0.84 | GPR84 (0.71) | HSD17B3GPR84PPARGPPARDPPARA | |
| Dodecanoate SCHEMBL10939868 | 0.84 | GPR84 (0.71) | HSD17B3GPR84PPARGPPARDPPARA | |
| Palmitic Acid SCHEMBL10942082 | 0.84 | GPR84 (0.71) | HSD17B3GPR84PPARGPPARDPPARA | |
| Octanoic Acid SCHEMBL10937199 | 0.84 | GPR84 (0.71) | HSD17B3GPR84PPARGPPARDPPARA | |
| Undecanoate SCHEMBL2382548 | 0.84 | GPR84 (0.71) | HSD17B3GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2992044-B1 | POLYOLEFIN PIPE | UPONOR INNOVATION AB (SE) | 2022-01-12 | — | — | EP | disclosed |
| US-10392496-B2 | Polyolefin pipe | UPONOR INNOVATION AB (SE) | 2019-08-27 | — | — | US | disclosed |
| US-20180258255-A1 | Polyolefin Pipe | UPONOR INNOVATION AB (SE) | 2018-09-13 | — | — | US | disclosed |
| US-9963573-B2 | Polyolefin pipe | UPONOR INNOVATION AB (SE) | 2018-05-08 | — | — | US | disclosed |
| US-20160130420-A1 | Polyolefin Pipe | UPONOR INNOVATION AB (SE) | 2016-05-12 | — | — | US | disclosed |
| EP-2992044-A1 | POLYOLEFIN PIPE | Uponor Innovation AB (SE) | 2016-03-09 | — | — | EP | disclosed |
| WO-2014177435-A1 | POLYOLEFIN PIPE | UPONOR INNOVATION AB (SE) | 2014-11-06 | — | — | WO | disclosed |