Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26691656 | 0.98 | FAAH (0.44) | FAAHKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL22872813 | 0.98 | FAAH (0.44) | FAAHKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL14240965 | 0.95 | ALDH1A1 (0.41) | FAAHKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL25063763 | 0.92 | HPGD (0.43) | FAAHKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL25591284 | 0.91 | EPHX2 (0.43) | FAAHKMT2AALDH1A1LMNAHPGD | |
| SCHEMBL21106554 | 0.89 | EPHX2 (0.45) | FAAHKMT2AALDH1A1LMNA | |
| SCHEMBL24935618 | 0.88 | HPGD (0.43) | FAAHKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL25063750 | 0.86 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL24935605 | 0.86 | ALDH1A1 (0.46) | FAAHKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19249122 | 0.84 | EPHX2 (0.43) | FAAHKMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020219650-A1 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 12 (CDK12) AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-10-29 | — | — | WO | disclosed |
| US-8877774-B2 | Compounds having muscarinic receptor antagonist and beta2 Adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-11-04 | — | — | US | disclosed |