Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | FPR3 | P25089 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1166830 | 0.82 | FPR2 (0.42) | FPR2DAGLAFPR3HRH3HDAC6 | |
| SCHEMBL19871354 | 0.82 | FPR2 (0.40) | FPR2DAGLAFPR3HRH3HDAC6 | |
| SCHEMBL9926019 | 0.81 | FPR2 (0.39) | FPR2DAGLAFPR3HRH3HDAC6 | |
| SCHEMBL13820314 | 0.81 | FPR2 (0.39) | FPR2DAGLAFPR3HRH3HDAC6 | |
| SCHEMBL346006 | 0.80 | CACNA1G (0.42) | DAGLAHRH3 | |
| SCHEMBL1706523 | 0.79 | DAGLA (0.40) | FPR2DAGLAFPR3HRH3HDAC6 | |
| SCHEMBL14076074 | 0.78 | FPR2 (0.45) | FPR2DAGLAFPR3HRH3HDAC6 | |
| SCHEMBL21333174 | 0.74 | DAGLA (0.52) | FPR2DAGLA | |
| SCHEMBL26728112 | 0.74 | — | — | |
| SCHEMBL1166849 | 0.73 | CYP1A2 (0.38) | FPR2DAGLAFPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877774-B2 | Compounds having muscarinic receptor antagonist and beta2 Adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-11-04 | — | — | US | disclosed |