SCHEMBL16213853

SCHEMBL16213853

CCCCCNC(C)c1nc(N)nc(Nc2cccc(S(=O)(=O)O)c2)n1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHAT P28329 2/20 0.38
ENPP3 O14638 1/20 0.38
ENPP1 P22413 1/20 0.38
ROCK1 Q13464 1/20 0.38
PDE5A O76074 5/20 0.37
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
CA9 Q16790 3/20 0.37
CA12 O43570 2/20 0.37
KCNH3 Q9ULD8 1/20 0.37
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
NOD1 Q9Y239 1/20 0.36
CDK1 P06493 2/20 0.35
KDR P35968 1/20 0.35
CASR P41180 2/20 0.35
CDK2 P24941 1/20 0.35
MTOR P42345 1/20 0.35
SMG1 Q96Q15 1/20 0.35
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15984410 0.83 KCNH3 (0.55) PDE5ACA1CA2CA9CA12
SCHEMBL17033141 0.79 NPC1 (0.43) PDE5ACA1CA2CA9CA12
SCHEMBL15984406 0.79 CA1 (0.54) CHATENPP3ENPP1PDE5ACA1
SCHEMBL16213866 0.79 SNCA (0.44) CHATENPP3ENPP1CA1CA2
SCHEMBL16213850 0.77 NPC1 (0.51) ROCK1NPC1RAB9ANOD1POLB
SCHEMBL16213863 0.74 CA1 (0.37) CHATENPP3ENPP1PDE5ACA1
SCHEMBL17808450 0.74 CA1 (0.44) CHATENPP3ENPP1ROCK1PDE5A
SCHEMBL14817406 0.74 CA9 (0.55) CHATENPP3ENPP1ROCK1CA1
SCHEMBL14817410 0.74 CA12 (0.44) CHATENPP3ENPP1ROCK1PDE5A
SCHEMBL17808448 0.73 KCNH3 (0.44) CHATENPP3ENPP1ROCK1PDE5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8876915-B2 Coloring composition and ink for inkjet recording FUJIFILM CORPORATION (JP) 2014-11-04 US disclosed