Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | FABP7 | O15540 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16214732 | 1.00 | FKBP1A (0.46) | FKBP1ATSHRALDH1A1FABP7FABP5 | |
| SCHEMBL16214759 | 0.89 | FKBP1A (0.43) | FKBP1ATSHRALDH1A1FABP7FABP5 | |
| SCHEMBL17365605 | 0.89 | FKBP1A (0.43) | FKBP1ATSHRALDH1A1FABP7FABP5 | |
| SCHEMBL17365553 | 0.89 | FKBP1A (0.43) | FKBP1ATSHRALDH1A1FABP7FABP5 | |
| SCHEMBL17365570 | 0.89 | FKBP1A (0.43) | FKBP1ATSHRALDH1A1FABP7FABP5 | |
| SCHEMBL16214731 | 0.85 | FKBP1A (0.45) | FKBP1ATSHRALDH1A1FABP7FABP5 | |
| SCHEMBL16214742 | 0.84 | SMN1; SMN2 (0.41) | FKBP1ATSHRALDH1A1FABP7FABP5 | |
| SCHEMBL31518977 | 0.83 | FABP7 (0.54) | FKBP1ATSHRALDH1A1FABP7FABP5 | |
| SCHEMBL522278 | 0.83 | FABP7 (0.54) | FKBP1ATSHRALDH1A1FABP7FABP5 | |
| SCHEMBL2703515 | 0.82 | FABP7 (0.55) | FKBP1ATSHRALDH1A1FABP7FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877749-B2 | Spirocyclic compounds as modulators of chemokine receptor activity | Bristol-Myers Squibbs Company (US) | 2014-11-04 | — | — | US | disclosed |