Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 10/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 10/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 6/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3707948 | 0.91 | ITGB1 (0.43) | ITGB1ITGA4MMP1MMEL1MME | |
| SCHEMBL6125680 | 0.84 | MMEL1 (0.48) | MMEL1MME | |
| SCHEMBL3699639 | 0.84 | MMEL1 (0.48) | MMEL1MME | |
| SCHEMBL3696881 | 0.83 | MME (0.43) | ITGB1ITGA4MMP1MMEL1MME | |
| SCHEMBL3701267 | 0.83 | MME (0.43) | ITGB1ITGA4MMP1MMEL1MME | |
| SCHEMBL7513252 | 0.81 | GPR34 (0.42) | MMEL1MMEF11 | |
| SCHEMBL7507623 | 0.81 | MME (0.45) | ITGB1ITGA4MMP1MME | |
| SCHEMBL3699806 | 0.80 | ITGB1 (0.46) | ITGB1ITGA4MMP1MMEL1MME | |
| SCHEMBL3699803 | 0.80 | ITGB1 (0.46) | ITGB1ITGA4MMP1MMEL1MME | |
| SCHEMBL3694682 | 0.79 | ITGB1 (0.40) | ITGB1ITGA4MMP1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877815-B2 | Substituted carbamoylcycloalkyl acetic acid derivatives as NEP | NOVARTIS AG (CH) | 2014-11-04 | — | — | US | disclosed |