Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.61 |
| ▸ | HPGDS | O60760 | 1/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13320691 | 0.89 | MEN1 (0.78) | ALDH1A1HPGDSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL16215255 | 0.89 | ALDH1A1 (0.71) | ALDH1A1HPGDSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL16215171 | 0.88 | ALDH1A1 (0.77) | ALDH1A1HPGDSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL16215205 | 0.84 | ALDH1A1 (0.85) | ALDH1A1HPGDSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL16215147 | 0.84 | ALDH1A1 (0.61) | ALDH1A1HPGDSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL16215257 | 0.84 | ALDH1A1 (0.61) | ALDH1A1HPGDSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL16215201 | 0.83 | ALDH1A1 (0.66) | ALDH1A1HPGDSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL16215245 | 0.83 | ALDH1A1 (0.53) | ALDH1A1HPGDSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL13352030 | 0.82 | PKM (0.59) | ALDH1A1HPGDSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL16215213 | 0.81 | ALDH1A1 (0.66) | ALDH1A1HPGDSMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2799427-A1 | Therapeutic compounds | Fibrotech Therapeutics PTY LTD (AU) | 2014-11-05 | — | — | EP | disclosed |