Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15178440 | 0.76 | CHRNB4 (0.43) | SNCAHTTCHRNB4CHRNA3TDP1 | |
| SCHEMBL27678811 | 0.74 | ERN1 (0.41) | SNCAHTTCHRNB4CHRNA3CAPN9 | |
| SCHEMBL28167738 | 0.72 | CHRNB4 (0.46) | SNCAHTTCHRNB4CHRNA3TDP1 | |
| SCHEMBL24453136 | 0.71 | AR (0.39) | CHRNB4CHRNA3TDP1CAPN9CASP3 | |
| SCHEMBL15178437 | 0.71 | CHRNB4 (0.36) | HTTCHRNB4CHRNA3ALDH1A1L3MBTL1 | |
| SCHEMBL30627997 | 0.67 | MEN1 (0.49) | HTTCHRNB4CHRNA3TDP1ALDH1A1 | |
| SCHEMBL19606362 | 0.67 | CHRNB4 (0.43) | SNCAHTTCHRNB4CHRNA3TDP1 | |
| SCHEMBL27388933 | 0.67 | ALDH1A1 (0.46) | HTTCHRNB4CHRNA3TDP1CAPN9 | |
| SCHEMBL27612518 | 0.67 | CHRNB4 (0.43) | SNCAHTTCHRNB4CHRNA3TDP1 | |
| SCHEMBL11427314 | 0.66 | PGR (0.72) | SNCACHRNB4CHRNA3TDP1CAPN9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2799431-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM Corporation (JP) | 2014-11-05 | — | — | EP | disclosed |