Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.71 |
| ▸ | NPC1 | O15118 | 9/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | PKM | P14618 | 3/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.56 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.56 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.53 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5022824 | 0.83 | RAB9A (0.71) | RAB9ANPC1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL3164310 | 0.83 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL14758512 | 0.83 | RAB9A (0.71) | RAB9ANPC1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL30354980 | 0.83 | RAB9A (0.71) | RAB9ANPC1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL28522547 | 0.80 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30354939 | 0.79 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL5025455 | 0.79 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL30362429 | 0.78 | MEN1 (0.72) | RAB9ANPC1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL30799158 | 0.78 | KMT2A (0.70) | RAB9ANPC1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL15205296 | 0.78 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140329863-A1 | NOVEL ANTIPRION COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-11-06 | — | — | US | disclosed |
| US-20140329863-A1 | NOVEL ANTIPRION COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140329863-A1 | NOVEL ANTIPRION COMPOUNDS | PRNP, PSEN1, PSEN2 | RAB9A 1779/4885NPC1 57/4885SMN1; SMN2 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.