Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.70 |
| ▸ | MEN1 | O00255 | 5/20 | 0.70 |
| ▸ | NPC1 | O15118 | 5/20 | 0.70 |
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | CASP3 | P42574 | 1/20 | 0.64 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.64 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.60 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.59 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.59 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.59 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739642 | 0.88 | KMT2A (0.86) | KMT2AMEN1NPC1RAB9AKCNK3 | |
| SCHEMBL8770869 | 0.85 | KMT2A (0.72) | KMT2AMEN1NPC1RAB9AKCNK3 | |
| SCHEMBL5375629 | 0.85 | NPC1 (0.72) | KMT2AMEN1NPC1RAB9AKCNK3 | |
| SCHEMBL3677300 | 0.85 | KMT2A (0.59) | KMT2AMEN1NPC1RAB9AKCNK3 | |
| SCHEMBL30643220 | 0.85 | MEN1 (0.88) | KMT2AMEN1NPC1RAB9AKCNK3 | |
| SCHEMBL6027951 | 0.85 | MEN1 (0.88) | KMT2AMEN1NPC1RAB9AKCNK3 | |
| SCHEMBL678688 | 0.84 | KMT2A (0.70) | KMT2AMEN1NPC1RAB9AKCNK3 | |
| SCHEMBL6802691 | 0.84 | KMT2A (0.78) | KMT2AMEN1NPC1RAB9AKCNK3 | |
| SCHEMBL6748120 | 0.84 | KMT2A (0.70) | KMT2AMEN1NPC1RAB9AKCNK3 | |
| SCHEMBL8361568 | 0.84 | KCNK3 (0.73) | KMT2AMEN1NPC1RAB9AKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050825-A1 | COMPOUNDS AS MLKL INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2024-03-14 | — | — | WO | disclosed |