SCHEMBL16218297

SCHEMBL16218297

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nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.54
▸ CCKAR P32238 11/20 0.41
▸ CCKBR P32239 11/20 0.41
▸ NOD1 Q9Y239 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16093424 1.00 GLP1R (0.54) GLP1RCCKARCCKBRNOD1
SCHEMBL19069662 1.00 GLP1R (0.54) GLP1RCCKARCCKBRNOD1
SCHEMBL16180974 0.93 GLP1R (0.54) GLP1RCCKARCCKBRNOD1
SCHEMBL16180949 0.93 GLP1R (0.51) GLP1RCCKARCCKBR
SCHEMBL16218301 0.93 GLP1R (0.54) GLP1RCCKARCCKBRNOD1
SCHEMBL19261654 0.93 GLP1R (0.53) GLP1RCCKARCCKBRNOD1
SCHEMBL16093454 0.92 GLP1R (0.51) GLP1RCCKARCCKBR
SCHEMBL16093425 0.92 GLP1R (0.51) GLP1RCCKARCCKBR
SCHEMBL21126547 0.88 GLP1R (0.54) GLP1RCCKARCCKBRNOD1
SCHEMBL16180955 0.88 GLP1R (0.52) GLP1RCCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140329750-A1 Growth Hormones with Prolonged In-Vivo Efficacy NOVO NORDISK HEALTHCARE AG (CH) 2014-11-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140329750-A1 Growth Hormones with Prolonged In-Vivo Efficacy GHRHR, GHITM, SHBG GLP1R 31/4885CCKAR 314/4885CCKBR 145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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