⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL163392 | 0.78 | — | — | |
| SCHEMBL162193 | 0.75 | — | — | |
| SCHEMBL70598 | 0.75 | SMN1; SMN2 (0.62) | — | |
| SCHEMBL9346702 | 0.75 | TDP1 (0.43) | — | |
| SCHEMBL782011 | 0.73 | — | — | |
| SCHEMBL1969273 | 0.73 | — | — | |
| SCHEMBL5719789 | 0.73 | — | — | |
| SCHEMBL20929043 | 0.73 | — | — | |
| SCHEMBL600362 | 0.73 | — | — | |
| SCHEMBL1928760 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113582971-B | Small molecule immunosuppressant, preparation method and application thereof | 北京康辰药业股份有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-114276328-A | Compound as small molecule immunosuppressant, preparation method and application thereof | 北京康辰药业股份有限公司 | 2022-04-05 | — | — | CN | claimed |
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-15 | — | — | US | claimed |
| CN-113582971-B | Small molecule immunosuppressant, preparation method and application thereof | 北京康辰药业股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-114276328-B | Compound as small molecule immunosuppressant, preparation method and application thereof | 北京康辰药业股份有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-114276328-A | Compound as small molecule immunosuppressant, preparation method and application thereof | 北京康辰药业股份有限公司 | 2022-04-05 | — | — | CN | disclosed |
| US-9856210-B2 | Pharmaceutical composition for prevention and treatment of amyotrophic lateral sclerosis | KYOTO UNIVERSITY (JP) | 2018-01-02 | — | — | US | disclosed |
| EP-2611437-B1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | UNIV KYOTO (JP) | 2017-03-29 | — | — | EP | disclosed |
| US-20130225642-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | KYOTO UNIVERSITY (JP) | 2013-08-29 | — | — | US | disclosed |
| EP-2611437-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | Kyoto University (JP) | 2013-07-10 | — | — | EP | disclosed |
| CN-101648891-B | Aryl cyclobutyl compound and application thereof in preparing weight-losing medicine | BEIJING JIASHI LIANBO PHARMACEUTICAL TECHNOLOGY CORP | 2012-11-28 | — | — | CN | disclosed |
| CN-1148387-A | Substd. aminoalkylaminopyridine | BYK GULDEN LOMBERG CHEM FAB (DE) | 1997-04-23 | — | — | CN | disclosed |
| EP-0731801-A1 | SUBSTITUTED AMINOALKYLAMINOPYRIDINES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1996-09-18 | — | — | EP | disclosed |
| WO-1995015324-A1 | SUBSTITUTED AMINOALKYLAMINOPYRIDINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1995-06-08 | — | — | WO | disclosed |
| US-4588817-A | Antibiotic nodusmicins | THE UPJOHN COMPANY (US) | 1986-05-13 | — | — | US | disclosed |
| US-4461903-A | Antibiotic nodusmicin derivatives | THE UPJOHN COMPANY (US) | 1984-07-24 | — | — | US | disclosed |
| US-4448970-A | ANTIBIOTICS, BACTERICIDES | THE UPJOHN COMPANY (US) | 1984-05-15 | — | — | US | disclosed |
| US-4363922-A | Esters of antibiotic nodusmicin | THE UPJOHN COMPANY (US) | 1982-12-14 | — | — | US | disclosed |
| US-4360683-A | Antibiotic nodusmicin derivatives | THE UPJOHN COMPANY (US) | 1982-11-23 | — | — | US | disclosed |
| US-4351769-A | Antibiotic composition of matter | THE UPJOHN COMPANY (US) | 1982-09-28 | — | — | US | disclosed |