SCHEMBL70598

SCHEMBL70598

O=C(O)c1c[nH]c(C(=O)O)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.62
NOTUM Q6P988 2/20 0.60
TDP1 Q9NUW8 2/20 0.58
RAB9A P51151 3/20 0.56
GAA P10253 1/20 0.56
NPC1 O15118 1/20 0.53
HSP90AA1 P07900 1/20 0.53
PKM P14618 1/20 0.53
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48
CA14 Q9ULX7 2/20 0.48
ALDH1A1 P00352 2/20 0.48
KDM4E B2RXH2 1/20 0.48
LMNA P02545 1/20 0.48
TP53 P04637 1/20 0.48
CA3 P07451 1/20 0.48
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28339344 0.98 SMN1; SMN2 (0.60) SMN1; SMN2NOTUMTDP1RAB9AGAA
SCHEMBL8284047 0.84 TDP1 (0.58) SMN1; SMN2NOTUMTDP1RAB9AGAA
SCHEMBL29159168 0.84 SMN1; SMN2 (0.56) SMN1; SMN2NOTUMTDP1RAB9AGAA
SCHEMBL20893876 0.81 SMN1; SMN2 (0.53) SMN1; SMN2NOTUMTDP1RAB9AGAA
SCHEMBL1664710 0.79 BAZ2B (0.67) SMN1; SMN2NOTUMTDP1RAB9AGAA
SCHEMBL7967223 0.79 SMN1; SMN2 (0.51) SMN1; SMN2NOTUMTDP1RAB9AGAA
SCHEMBL2419793 0.79 ALDH1A1 (0.68) SMN1; SMN2TDP1RAB9AGAANPC1
SCHEMBL10939397 0.79 ALDH1A1 (0.58) SMN1; SMN2NOTUMTDP1RAB9AGAA
SCHEMBL19101990 0.79 ALDH1A1 (0.58) SMN1; SMN2NOTUMTDP1RAB9AGAA
SCHEMBL2221019 0.79 TDP1 (0.67) SMN1; SMN2NOTUMTDP1RAB9AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12157094-B2 Gas separation method with multilayer membrane KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-12-03 US claimed
US-12138596-B2 Method for separating carbon dioxide and methane KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-11-12 US claimed
US-12102966-B2 CO2 gas enrichment method KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-10-01 US claimed
US-12102967-B2 Method for separating a gas stream to isolate carbon dioxide KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-10-01 US claimed
US-20240278188-A1 METHOD FOR SEPARATING CARBON DIOXIDE AND METHANE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-08-22 US claimed
US-20240278190-A1 GAS SEPARATION METHOD WITH MULTILAYER MEMBRANE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-08-22 US claimed
US-20240269622-A1 METHOD FOR SEPARATING A GAS STREAM TO ISOLATE CARBON DIOXIDE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-08-15 US claimed
US-20240226816-A1 CO2 GAS ENRICHMENT METHOD KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-07-11 US claimed
US-11969694-B2 Method for separating a gas mixture KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-04-30 US claimed
US-11964240-B2 Gas filter for separating gaseous compositions KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-04-23 US claimed
EP-1877412-A1 ZEOLITE-LIKE METAL ORGANIC FRAMEWORKS (ZMOFS): MODULAR APPROACH TO THE SYNTHESIS OF ORGANIC-INORGANIC HYBRID POROUS MATERIALS HAVING A ZEOLITE LIKE TOPOLOGY UNIVERSITY OF SOUTH FLORIDA (US) 2008-01-16 EP claimed
US-20060287190-A1 Zeolite-like metal organic frameworks (ZMOFS): modular approach to the synthesis of organic-inorganic hybrid porous materials having a zeolite like topology UNIVERSITY OF SOUTH FLORIDA 2006-12-21 US claimed
WO-2006116340-A1 ZEOLITE-LIKE METAL ORGANIC FRAMEWORKS (ZMOFS): MODULAR APPROACH TO THE SYNTHESIS OF ORGANIC-INORGANIC HYBRID POROUS MATERIALS HAVING A ZEOLITE LIKE TOPOLOGY UNIVERSITY OF SOUTH FLORIDA (US) 2006-11-02 WO claimed
US-6924276-B2 Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors WARNER-LAMBERT COMPANY (US) 2005-08-02 US claimed
EP-1440068-A1 ACYL DIHYDRO PYRROLE DERIVATIVES AS HCV INHIBITORS GLAXO GROUP LIMITED (GB) 2004-07-28 EP claimed
US-20030087924-A1 Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors SORENSON RODERICK JOSEPH (US) 2003-05-08 US claimed
WO-2003037893-A1 ACYL DIHYDRO PYRROLE DERIVATIVES AS HCV INHIBITORS GLAXO GROUP LIMITED (GB) 2003-05-08 WO claimed
EP-1291345-A1 Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors WARNER-LAMBERT COMPANY (US) 2003-03-12 EP claimed
EP-1211941-A1 SELECTIVE HERBICIDES ON THE BASIS OF A SUBSTITUTED PHENYLSULFONYLAMINOCARBONYLTRIAZOLINONE AND SAFENERS Bayer Aktiengesellschaft (DE) 2002-06-12 EP claimed
WO-2001015533-A1 SELECTIVE HERBICIDES ON THE BASIS OF A SUBSTITUTED PHENYLSULFONYLAMINOCARBONYLTRIAZOLINONE AND SAFENERS BAYER AKTIENGESELLSCHAFT (DE) 2001-03-08 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030087924-A1 Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors MMP13, MMP3, MMP9 SMN1; SMN2 3410/4885NOTUM 2612/4885TDP1 1854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.