Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SELL | P14151 | 1/20 | 0.43 |
| ▸ | SELP | P16109 | 1/20 | 0.43 |
| ▸ | FUT4 | P22083 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9658601 | 0.98 | TDP1 (0.42) | TDP1KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL15100201 | 0.81 | APP (0.39) | HPGDGAAAPPDAOMEN1 | |
| SCHEMBL18473811 | 0.78 | ALDH1A1 (0.45) | TDP1KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL13467617 | 0.76 | BRD4 (0.44) | TDP1CA9APPDAOMEN1 | |
| SCHEMBL9875866 | 0.76 | ALDH1A1 (0.47) | TDP1KDM4EALDH1A1MAPK1LMNA | |
| SCHEMBL162194 | 0.75 | — | — | |
| SCHEMBL20822006 | 0.74 | SMN1; SMN2 (0.40) | TDP1KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL10673588 | 0.73 | DAO (0.33) | TDP1KDM4EAPPDAOKMT2A | |
| SCHEMBL14818674 | 0.72 | SMN1; SMN2 (0.39) | TDP1KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL15764332 | 0.72 | CA12 (0.44) | TDP1KDM4ESMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300497-A | Broad spectrum antibiotics and bactericides; stable to beta-lactamase; effective against antibiotic-resistant bacteria | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5185330-A | Penicillins/ad/ | TOYAMA CHEMICAL CO., LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| US-5106977-A | Intermediates for a process for making 2-oxo-1-[[(substituted sulfonyl)-amino]carbonyl]azetidines | E. R. SQUIBB & SONS, INC. (US) | 1992-04-21 | — | — | US | disclosed |
| US-4980465-A | Process for making 2-oxo-1-[[(substituted sulfonyl)-amino]carbonyl)] azetidines and intermediates used therein | E. R. SQUIBB & SONS, INC. (US) | 1990-12-25 | — | — | US | disclosed |
| US-4889930-A | Process for making 2-oxo-1-((substituted sulfonyl)amino)carbonzyl)azetidines and intermediates used therein | E. R. SQUIBB & SONS, INC. (US) | 1989-12-26 | — | — | US | disclosed |
| EP-0321844-A2 | Process for making 2-oxo-1-(((substituted sulfonyl)-amino)carbonyl)azetidines and intermediates used therein | E.R. Squibb & Sons, Inc. (US) | 1989-06-28 | — | — | EP | disclosed |
| US-4743685-A | 2-oxo-1-[[(substituted sulfonyl)amino]carbonyl]azetidines | E. R. SQUIBB & SONS, INC. (US) | 1988-05-10 | — | — | US | disclosed |
| CN-86106980-A | The alkylsulfonyl that 2-oxo-1-{[(replaces)-and amino] carbonyl } azetidine-typed | — | 1987-04-08 | — | — | CN | disclosed |