SCHEMBL16219620

SCHEMBL16219620

CC1(C)c2cc(N(c3ccccc3)c3ccc(-c4ccccc4)cc3)ccc2-c2c1cc(-c1ccc(N(c3ccccc3)c3ccc(-c4ccccc4)cc3)cc1)c1ccccc21

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
CTNNB1 P35222 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
GPR84 Q9NQS5 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17153677 0.99 MEN1 (0.32) MEN1USP2ALDH1A1MAPTMAPK1
SCHEMBL16219605 0.97 ALDH1A1 (0.31) MEN1USP2ALDH1A1MAPTMAPK1
SCHEMBL15505887 0.95 ALDH1A1 (0.31) MEN1USP2ALDH1A1MAPTMAPK1
SCHEMBL20466641 0.95 PDK2 (0.33) MEN1USP2ALDH1A1MAPTMAPK1
SCHEMBL20466654 0.95 PDK2 (0.33) MEN1USP2ALDH1A1MAPTMAPK1
SCHEMBL15505857 0.94 MEN1 (0.31) MEN1USP2ALDH1A1MAPTMAPK1
SCHEMBL16219664 0.94 PDK2 (0.31) MEN1USP2ALDH1A1MAPTMAPK1
SCHEMBL20466652 0.94 PDK2 (0.33) MEN1USP2ALDH1A1MAPTMAPK1
SCHEMBL20466642 0.93 PDK2 (0.36)
SCHEMBL16219604 0.93 PDK2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9082987-B2 Benzofluorene-based compounds and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-07-14 US disclosed
US-9082987-B2 Benzofluorene-based compounds and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-07-14 US disclosed
US-20140326961-A1 BENZOFLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-11-06 US disclosed
US-20140326961-A1 BENZOFLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-11-06 US disclosed