SCHEMBL16219664

SCHEMBL16219664

CC1(C)c2cc(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)ccc2-c2c1cc(-c1ccc(N(c3ccccc3)c3ccccc3)cc1)c1ccccc21

nearest known ligand 0.31

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.31
GPR84 Q9NQS5 1/20 0.30
ALDH1A1 P00352 2/20 0.30
MAPT P10636 2/20 0.30
TDP1 Q9NUW8 2/20 0.30
L3MBTL1 Q9Y468 2/20 0.30
KDM4E B2RXH2 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
MEN1 O00255 1/20 0.30
USP2 O75604 1/20 0.30
MAPK1 P28482 1/20 0.30
CTNNB1 P35222 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20466641 0.99 PDK2 (0.33) PDK2GPR84ALDH1A1MAPTTDP1
SCHEMBL20466654 0.99 PDK2 (0.33) PDK2GPR84ALDH1A1MAPTTDP1
SCHEMBL20466652 0.97 PDK2 (0.33) PDK2GPR84ALDH1A1MAPTTDP1
SCHEMBL16219620 0.94 MEN1 (0.32) GPR84ALDH1A1MAPTTDP1L3MBTL1
SCHEMBL16219605 0.93 ALDH1A1 (0.31) PDK2GPR84ALDH1A1MAPTTDP1
SCHEMBL17153677 0.92 MEN1 (0.32) GPR84ALDH1A1MAPTTDP1L3MBTL1
SCHEMBL20466642 0.92 PDK2 (0.36) PDK2
SCHEMBL358382 0.92 ALDH1A1 (0.33) GPR84ALDH1A1MAPTTDP1L3MBTL1
SCHEMBL16219731 0.92 ACACA (0.32) GPR84
SCHEMBL16219632 0.91 RXRA (0.30) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9082987-B2 Benzofluorene-based compounds and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-07-14 US disclosed
US-9082987-B2 Benzofluorene-based compounds and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-07-14 US disclosed
US-20140326961-A1 BENZOFLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-11-06 US disclosed
US-20140326961-A1 BENZOFLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-11-06 US disclosed