Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.68 |
| ▸ | CA2 | P00918 | 5/20 | 0.68 |
| ▸ | CA5A | P35218 | 4/20 | 0.68 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.68 |
| ▸ | FLT3 | P36888 | 3/20 | 0.49 |
| ▸ | MIF | P14174 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29158522 | 0.90 | CA1 (0.68) | CA1CA2CA5ACA5BFLT3 | |
| SCHEMBL28319781 | 0.84 | CA1 (0.61) | CA1CA2CA5ACA5BFLT3 | |
| SCHEMBL18023900 | 0.83 | PTGS2 (0.58) | CA1CA2CA5ACA5BFLT3 | |
| SCHEMBL28319778 | 0.83 | FLT3 (0.67) | CA1CA2CA5ACA5BFLT3 | |
| SCHEMBL1908790 | 0.81 | MIF (0.50) | CA1CA2CA5ACA5BMIF | |
| SCHEMBL12420382 | 0.79 | FLT3 (0.49) | CA1CA2CA5ACA5BFLT3 | |
| SCHEMBL27984092 | 0.79 | CA12 (0.53) | CA1CA2CA5ACA5BFLT3 | |
| SCHEMBL5705130 | 0.77 | CA1 (0.49) | CA1CA2CA5ACA5BFLT3 | |
| SCHEMBL19454747 | 0.77 | BRD4 (0.53) | CA1CA2CA5ACA5BFLT3 | |
| SCHEMBL12420373 | 0.76 | FLT3 (0.69) | CA1CA2CA5ACA5BFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106588787-A | Arylformyl group-containing 1,2,3-triazole ligand, and preparation method and application thereof | 昆明理工大学 | 2017-04-26 | — | — | CN | claimed |
| CN-106588787-B | A kind of application of the triazole of 1,2,3- containing sweet-smelling formacyl ligand | 昆明理工大学 | 2019-09-27 | — | — | CN | disclosed |
| CN-106588788-B | The method of one pot of two-step method synthesis 1,2,3- triazole compound | 河南师范大学 | 2019-07-16 | — | — | CN | disclosed |
| CN-104945341-B | A kind of method of the triazole compound of three components one pot process 1,2,3 | 河南师范大学 | 2018-03-02 | — | — | CN | disclosed |
| EP-2991997-B1 | TRANSITION METAL COMPLEXES WITH CARBENE LIGANDS AND THE USE THEREOF IN OLEDS | UDC IRELAND LTD (IE) | 2018-02-21 | — | — | EP | disclosed |
| CN-106588787-A | Arylformyl group-containing 1,2,3-triazole ligand, and preparation method and application thereof | 昆明理工大学 | 2017-04-26 | — | — | CN | disclosed |
| US-20160072081-A1 | Transition metal complexes with carbene ligands and the use thereof in OLEDs | BASF SE (DE) | 2016-03-10 | — | — | US | disclosed |
| US-20160072081-A1 | Transition metal complexes with carbene ligands and the use thereof in OLEDs | BASF SE (DE) | 2016-03-10 | — | — | US | disclosed |
| CN-104945341-A | Method for synthesizing 1,2,3-triazole compound through three components in one pot | UNIV HENAN NORMAL | 2015-09-30 | — | — | CN | disclosed |
| WO-2014177518-A1 | TRANSITION METAL COMPLEXES WITH CARBENE LIGANDS AND THE USE THEREOF IN OLEDS | BASF SE (DE) | 2014-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160072081-A1 | Transition metal complexes with carbene ligands and the use thereof in OLEDs | OCIAD1, OCIAD2, TRPM6 | CA1 1901/4885CA2 1012/4885CA5A 2262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.