Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA5A | P35218 | 3/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4240353 | 0.84 | MIF (0.49) | MIFCA1CA2CA5ACA5B | |
| SCHEMBL23288093 | 0.82 | PIK3CA (0.49) | MIFCA1CA2CA5ACA5B | |
| SCHEMBL16220810 | 0.81 | CA1 (0.68) | MIFCA1CA2CA5ACA5B | |
| SCHEMBL27984092 | 0.81 | CA12 (0.53) | MIFCA1CA2CA5ACA5B | |
| SCHEMBL12420382 | 0.81 | FLT3 (0.49) | MIFCA1CA2CA5ACA5B | |
| SCHEMBL28661840 | 0.80 | NOTUM (0.57) | MIFCA1CA2CA5ACA5B | |
| SCHEMBL4550718 | 0.78 | HSP90AA1 (0.51) | MIFCA1CA2CA5ACA5B | |
| SCHEMBL23086229 | 0.77 | HSD17B1 (0.74) | MIFCA1CA2CA5ACA5B | |
| SCHEMBL1119554 | 0.77 | PTGS2 (0.66) | MIFCA1CA2CA5ACA5B | |
| SCHEMBL23430997 | 0.77 | MAPT (0.77) | MIFCA1CA2CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115009-B2 | UV-absorbers for ophthalmic lens materials | NOVARTIS AG (CH) | 2012-02-14 | — | — | US | disclosed |
| US-20110105765-A1 | UV-ABSORBERS FOR OPHTHALMIC LENS MATERIALS | ALCON, INC. (CH) | 2011-05-05 | — | — | US | disclosed |
| US-7909458-B2 | UV-absorbers for ophthalmic lens materials | ALCON, INC. (CH) | 2011-03-22 | — | — | US | disclosed |
| US-20100207068-A1 | PROCESS FOR PRODUCING PURIFIED SYNTHESIS GAS FROM SYNTHESIS GAS COMPRISING TRACE AMOUNTS OF SULPHUR CONTAMINANTS WITH A METAL-ORGANIC FRAMEWORK | SHELL OIL COMPANY | 2010-08-19 | — | — | US | disclosed |
| US-20080266519-A1 | UV-ABSORBERS FOR OPHTHALMIC LENS MATERIALS | ALCON RESEARCH, LTD. (US) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080266519-A1 | UV-ABSORBERS FOR OPHTHALMIC LENS MATERIALS | UACA, CRYZ, CRYAA | MIF 567/4885CA1 2622/4885CA2 3213/4885 |
| US-20110105765-A1 | UV-ABSORBERS FOR OPHTHALMIC LENS MATERIALS | UACA, CRYZ, CRYAA | MIF 567/4885CA1 2622/4885CA2 3213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.