Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8644706 | 0.81 | KDM4E (0.38) | MEN1KMT2ATDP1KDM4ETSHR | |
| SCHEMBL7771345 | 0.81 | KMT2A (0.39) | MEN1KMT2ATDP1KDM4EALDH1A1 | |
| SCHEMBL1099822 | 0.78 | TSHR (0.41) | KMT2ATDP1KDM4ETSHRALDH1A1 | |
| SCHEMBL753675 | 0.74 | ALDH1A1 (0.48) | KMT2ATDP1KDM4ETSHRALDH1A1 | |
| SCHEMBL128319 | 0.73 | CYP1A2 (0.58) | MEN1KMT2ATDP1KDM4ETSHR | |
| SCHEMBL31389208 | 0.73 | CYP1A2 (0.58) | MEN1KMT2ATDP1KDM4ETSHR | |
| SCHEMBL8529933 | 0.72 | ALDH1A1 (0.43) | KMT2ATDP1KDM4ETSHRALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL29137499 | 0.71 | CYP1A2 (0.55) | MEN1KMT2ATDP1KDM4ETSHR | |
| SCHEMBL125358 | 0.71 | — | — | |
| SCHEMBL29370019 | 0.70 | CYP1A2 (0.48) | MEN1KMT2ATDP1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150140088-A1 | SPIROSTEROID SYSTEMS ACTING AS NEUROPROTECTIVE AND ANTI-INFLAMMATORY AGENTS | CENTRO DE INVESTIGACION Y DESARROLLO DE LOS MEDICAMENTOS (CIDEM) (CU) | 2015-05-21 | — | — | US | disclosed |
| EP-2801581-A1 | SPIROSTEROIDAL SYSTEMS HAVING NEUROACTIVE, ANTI-INFLAMMATORY EFFECTS | Centro de Investigación y Desarrollo de los Medicamentos (CIDEM) (US) | 2014-11-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150140088-A1 | SPIROSTEROID SYSTEMS ACTING AS NEUROPROTECTIVE AND ANTI-INFLAMMATORY AGENTS | NR3C2, GRIN3A, CYP46A1 | MEN1 4497/4885KMT2A 3539/4885TDP1 2549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.