Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 4/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4372772 | 0.83 | PBRM1 (0.37) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 | |
| SCHEMBL1893396 | 0.81 | PARP1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL6160784 | 0.78 | GAA (0.47) | ALOX15KDM4EHSD17B10CA12CA1 | |
| SCHEMBL10412258 | 0.78 | HSP90AB1 (0.39) | ALDH1A1KDM4EHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL1098615 | 0.78 | TSHR (0.50) | ALDH1A1ALOX15KDM4EHSD17B10CA1 | |
| SCHEMBL4024749 | 0.78 | KMT2A (0.46) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL1100763 | 0.78 | GAA (0.48) | HPGDHDAC8POLB | |
| SCHEMBL3844824 | 0.76 | ALDH1A1 (0.50) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 | |
| SCHEMBL160051 | 0.76 | ALDH1A1 (0.50) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 | |
| SCHEMBL12521035 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430013-A1 | HETEROARYL COMPOUNDS AS PIKK INHIBITORS | Amgen, Inc (US) | 2012-03-21 | — | — | EP | claimed |
| WO-2010132598-A1 | HETEROARYL COMPOUNDS AS PIKK INHIBITORS | AMGEN INC. (US) | 2010-11-18 | — | — | WO | claimed |
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| US-20070161674-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2007-07-12 | — | — | US | claimed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | claimed |
| US-7160933-B2 | Image quality and durability; scratch and smudge resistance; water, humectant and particles comprised of water insoluble dye and polymer phase associated with costabilizer | EASTMAN KODAK COMPANY (US) | 2007-01-09 | — | — | US | claimed |
| US-20060049052-A1 | Ampholytic buffer having high buffering capacity and high conductivity in isoelectric form | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2006-03-09 | — | — | US | claimed |
| US-20040186198-A1 | Stable ink jet ink composition and printing method | EASTMAN KODAK COMPANY | 2004-09-23 | — | — | US | claimed |
| EP-0277725-A2 | 4-Aryl-N-[2-(dialkylamino and heterocyclicamino) alkyl]-1-piperazinecarboxamides and their use as anti allergy agents | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-08-10 | — | — | EP | claimed |
| EP-4373865-A1 | CATALYTIC HYDROGENOLYSIS OF A POLYMER | Northwestern University (US) | 2024-05-29 | — | — | EP | disclosed |
| CN-113896607-B | Olefin oligomerization process using a catalyst comprising a chromium complex having a phosphacycle-containing ligand | 陶氏环球技术有限责任公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-117651723-A | Catalytic hydrogenolysis of polymers | 西北大学 | 2024-03-05 | — | — | CN | disclosed |
| US-11896965-B2 | Chromium complex and catalyst therefrom | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-02-13 | — | — | US | disclosed |
| US-20230112954-A1 | CHROMIUM COMPLEX AND CATALYST THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-04-13 | — | — | US | disclosed |
| EP-0423742-A2 | Silver halide color reversal photographic photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-04-24 | — | — | EP | disclosed |
| EP-0423693-A2 | Silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-04-24 | — | — | EP | disclosed |
| EP-0391405-A2 | Silver halide photographic material and method for processing thereof | FUJI PHOTO FILM CO., LTD. (JP) | 1990-10-10 | — | — | EP | disclosed |
| EP-0337490-A2 | Silver halide light-sensitive photographic material | Fuji Photo Film Co., Ltd. (JP) | 1989-10-18 | — | — | EP | disclosed |
| EP-0334593-A1 | Chiral azetidinone epoxides | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1989-09-27 | — | — | EP | disclosed |
| US-4317946-A | IN THE PRESENCE OF A RUTHENIUM CATALYST | THE HALCON SD GROUP, INC. (US) | 1982-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230112954-A1 | CHROMIUM COMPLEX AND CATALYST THEREFROM | OXER1, LIG1, PICALM | ALDH1A1 4013/4885ALOX15 19/4885KDM4E 2781/4885 |
| US-20060049052-A1 | Ampholytic buffer having high buffering capacity and high conductivity in isoelectric form | ALPP, CA2, CA1 | ALDH1A1 4582/4885ALOX15 4140/4885KDM4E 4802/4885 |
| US-11896965-B2 | Chromium complex and catalyst therefrom | OXER1, LIG1, PICALM | ALDH1A1 4013/4885ALOX15 19/4885KDM4E 2781/4885 |
| US-20070161674-A1 | Certain chemical entities, compositions, and methods | TP53, VHL, RB1 | ALDH1A1 258/4885ALOX15 766/4885KDM4E 4110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.