Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16223359 | 0.87 | MAPT (0.63) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL16245570 | 0.86 | MAPT (0.61) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL16245623 | 0.81 | GAA (0.58) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL16223234 | 0.80 | MAPT (0.48) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL16223194 | 0.79 | MAPT (0.50) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL16245627 | 0.79 | MAPT (0.50) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL16245578 | 0.79 | MAPT (0.50) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL16245908 | 0.79 | ITGA4 (0.52) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL16229906 | 0.79 | MAPT (0.50) | MAPTKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL16223148 | 0.77 | TDP1 (0.58) | MAPTKMT2AALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014180544-A1 | HYDANTOINE DERIVATIVES AS CD38 INHIBITORS | SANOFI (FR) | 2014-11-13 | — | — | WO | claimed |
| EP-2801573-A1 | Hydantoine derivatives as CD38 inhibitors | SANOFI (FR) | 2014-11-12 | — | — | EP | claimed |