SCHEMBL16223271

SCHEMBL16223271

CC(C)N(C(=N)C(F)(F)F)C(C)C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22143103 0.76
SCHEMBL16223205 0.74 ALDH1A1 (0.37) ALDH1A1
SCHEMBL14999389 0.69 ALDH1A1 (0.31) ALDH1A1
SCHEMBL7860374 0.67
SCHEMBL27687843 0.67
SCHEMBL29556546 0.67
SCHEMBL31182127 0.67
SCHEMBL6057228 0.67 CHRM2 (0.38) ALDH1A1
SCHEMBL11102471 0.65 ALDH1A1 (0.32) ALDH1A1
Phosphine SCHEMBL28910692 0.63 ALDH1A1 (0.31) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11767376-B2 Catalyst mixture ARLANXEO NETHERLANDS B.V. (NL) 2023-09-26 US disclosed
US-11578148-B2 Metal complex comprising amidine and thiophene fused cyclopentadienyl ligands ARLANXEO NETHERLANDS B.V. 2023-02-14 US disclosed
US-11560394-B2 Metal complex comprising amidine and indole fused cyclopentadienyl ligands ARLANXEO NETHERLANDS B.V. 2023-01-24 US disclosed
US-20220056162-A1 CATALYST MIXTURE ARLANXEO NETHERLANDS B.V. (NL) 2022-02-24 US disclosed
EP-3732183-B1 METAL COMPLEX COMPRISING AMIDINE AND THIOPHENE FUSED CYCLOPENTADIENYL LIGANDS Arlanxeo Netherlands Bv (NL) 2021-10-20 EP disclosed
EP-3853265-A1 CATALYST MIXTURE Arlanxeo Netherlands B.V. (NL) 2021-07-28 EP disclosed
US-20210087305-A1 METAL COMPLEX COMPRISING AMIDINE AND THIOPHENE FUSED CYCLOPENTADIENYL LIGANDS ARLANXEO NETHERLANDS B.V. (NL) 2021-03-25 US disclosed
EP-3781582-A1 METAL COMPLEX COMPRISING AMIDINE AND INDOLE FUSED CYCLOPENTADIENYL LIGANDS Arlanxeo Netherlands B.V. (NL) 2021-02-24 EP disclosed
EP-3732183-A1 METAL COMPLEX COMPRISING AMIDINE AND THIOPHENE FUSED CYCLOPENTADIENYL LIGANDS Arlanxeo Netherlands B.V. (NL) 2020-11-04 EP disclosed
EP-3334768-B1 CATALYST SYSTEM Arlanxeo Netherlands Bv (NL) 2020-05-27 EP disclosed
US-10316113-B2 Catalyst system ARLANXEO NETHERLANDS B.V. (NL) 2019-06-11 US disclosed
US-20180237553-A1 CATALYST SYSTEM ARLANXEO NETHERLANDS B.V. (NL) 2018-08-23 US disclosed
EP-3334768-A1 CATALYST SYSTEM Arlanxeo Netherlands B.V. (NL) 2018-06-20 EP disclosed
EP-3272761-A1 METALL COMPLEX COMPRISING AMIDINE AND SUBSTITUTED CYCLOPENTADIENYL LIGANDS Arlanxeo Netherlands B.V. (NL) 2018-01-24 EP disclosed
US-20170240663-A1 METAL COMPLEX COMPRISING AMIDINE AND SUBSTITUTED CYCLOPENTADIENYL LIGANDS ARLANXEO NETHERLANDS B.V. (NL) 2017-08-24 US disclosed
EP-3194412-A1 METAL COMPLEX COMPRISING AMIDINE AND SUBSTITUTED CYCLOPENTADIENYL LIGANDS Arlanxeo Netherlands B.V. (NL) 2017-07-26 EP disclosed
WO-2017029141-A1 CATALYST SYSTEM ARLANXEO NETHERLANDS B.V. (NL) 2017-02-23 WO disclosed
EP-2801579-B1 Metal complex with a Lewis base ligand Arlanxeo Netherlands Bv (NL) 2016-10-19 EP disclosed
WO-2016041818-A1 METAL COMPLEX COMPRISING AMIDINE AND SUBSTITUTED CYCLOPENTADIENYL LIGANDS LANXESS ELASTOMERS B.V. (NL) 2016-03-24 WO disclosed
EP-2801579-A1 Metal complex with a Lewis base ligand Lanxess Elastomers B.V. (NL) 2014-11-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210087305-A1 METAL COMPLEX COMPRISING AMIDINE AND THIOPHENE FUSED CYCLOPENTADIENYL LIGANDS AP3M1, AP2M1, AP1M1 ALDH1A1 4736/4885
US-11560394-B2 Metal complex comprising amidine and indole fused cyclopentadienyl ligands C5, C1S, CLIC4 ALDH1A1 4269/4885
US-20170240663-A1 METAL COMPLEX COMPRISING AMIDINE AND SUBSTITUTED CYCLOPENTADIENYL LIGANDS AP2M1, AP1M1, STAMBP ALDH1A1 4400/4885
US-11578148-B2 Metal complex comprising amidine and thiophene fused cyclopentadienyl ligands AP3M1, AP2M1, AP1M1 ALDH1A1 4736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.