⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22143328 | 0.75 | — | — | |
| SCHEMBL1106487 | 0.72 | — | — | |
| SCHEMBL22143103 | 0.71 | — | — | |
| SCHEMBL21737586 | 0.68 | — | — | |
| SCHEMBL16223271 | 0.67 | ALDH1A1 (0.31) | — | |
| SCHEMBL18804388 | 0.67 | — | — | |
| Trifluoroacetic Acid SCHEMBL11789184 | 0.65 | ALDH1A1 (0.30) | — | |
| Trifluoroacetic Acid SCHEMBL4147574 | 0.65 | ALDH1A1 (0.30) | — | |
| SCHEMBL18804390 | 0.65 | — | — | |
| SCHEMBL18647232 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767376-B2 | Catalyst mixture | ARLANXEO NETHERLANDS B.V. (NL) | 2023-09-26 | — | — | US | disclosed |
| US-11578148-B2 | Metal complex comprising amidine and thiophene fused cyclopentadienyl ligands | ARLANXEO NETHERLANDS B.V. | 2023-02-14 | — | — | US | disclosed |
| US-11560394-B2 | Metal complex comprising amidine and indole fused cyclopentadienyl ligands | ARLANXEO NETHERLANDS B.V. | 2023-01-24 | — | — | US | disclosed |
| US-20220056162-A1 | CATALYST MIXTURE | ARLANXEO NETHERLANDS B.V. (NL) | 2022-02-24 | — | — | US | disclosed |
| EP-3732183-B1 | METAL COMPLEX COMPRISING AMIDINE AND THIOPHENE FUSED CYCLOPENTADIENYL LIGANDS | Arlanxeo Netherlands Bv (NL) | 2021-10-20 | — | — | EP | disclosed |
| EP-3853265-A1 | CATALYST MIXTURE | Arlanxeo Netherlands B.V. (NL) | 2021-07-28 | — | — | EP | disclosed |
| US-20210087305-A1 | METAL COMPLEX COMPRISING AMIDINE AND THIOPHENE FUSED CYCLOPENTADIENYL LIGANDS | ARLANXEO NETHERLANDS B.V. (NL) | 2021-03-25 | — | — | US | disclosed |
| EP-3781582-A1 | METAL COMPLEX COMPRISING AMIDINE AND INDOLE FUSED CYCLOPENTADIENYL LIGANDS | Arlanxeo Netherlands B.V. (NL) | 2021-02-24 | — | — | EP | disclosed |
| EP-3732183-A1 | METAL COMPLEX COMPRISING AMIDINE AND THIOPHENE FUSED CYCLOPENTADIENYL LIGANDS | Arlanxeo Netherlands B.V. (NL) | 2020-11-04 | — | — | EP | disclosed |
| WO-2020132269-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES AND SUBSTITUTED PURINES AND THEIR USE AS UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 1 (USP1) INHIBITORS | KSQ Therapeutics, Inc. (US) | 2020-06-25 | — | — | WO | disclosed |
| EP-3272761-A1 | METALL COMPLEX COMPRISING AMIDINE AND SUBSTITUTED CYCLOPENTADIENYL LIGANDS | Arlanxeo Netherlands B.V. (NL) | 2018-01-24 | — | — | EP | disclosed |
| US-20170240663-A1 | METAL COMPLEX COMPRISING AMIDINE AND SUBSTITUTED CYCLOPENTADIENYL LIGANDS | ARLANXEO NETHERLANDS B.V. (NL) | 2017-08-24 | — | — | US | disclosed |
| EP-3194412-A1 | METAL COMPLEX COMPRISING AMIDINE AND SUBSTITUTED CYCLOPENTADIENYL LIGANDS | Arlanxeo Netherlands B.V. (NL) | 2017-07-26 | — | — | EP | disclosed |
| WO-2017029141-A1 | CATALYST SYSTEM | ARLANXEO NETHERLANDS B.V. (NL) | 2017-02-23 | — | — | WO | disclosed |
| US-9546233-B2 | Metal complex with a lewis base ligand | ARLANXEO NETHERLANDS B.V. (NL) | 2017-01-17 | — | — | US | disclosed |
| EP-2801579-B1 | Metal complex with a Lewis base ligand | Arlanxeo Netherlands Bv (NL) | 2016-10-19 | — | — | EP | disclosed |
| US-20160115265-A1 | METAL COMPLEX WITH A LEWIS BASE LIGAND | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 2016-04-28 | — | — | US | disclosed |
| WO-2016041818-A1 | METAL COMPLEX COMPRISING AMIDINE AND SUBSTITUTED CYCLOPENTADIENYL LIGANDS | LANXESS ELASTOMERS B.V. (NL) | 2016-03-24 | — | — | WO | disclosed |
| EP-2801579-A1 | Metal complex with a Lewis base ligand | Lanxess Elastomers B.V. (NL) | 2014-11-12 | — | — | EP | disclosed |
| WO-2001057947-A1 | USE OF AMIDINES | SOLVAY FLUOR UND DERIVATE GMBH (DE) | 2001-08-09 | — | — | WO | disclosed |