Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | COMT | P21964 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10211855 | 0.91 | ALDH1A1 (0.62) | ALDH1A1KDM4EPOLBTSHRSMN1; SMN2 | |
| SCHEMBL20965553 | 0.90 | ALDH1A1 (0.62) | ALDH1A1KDM4EPOLBTSHRSMN1; SMN2 | |
| SCHEMBL18389944 | 0.90 | ALDH1A1 (0.62) | ALDH1A1KDM4EPOLBTSHRSMN1; SMN2 | |
| SCHEMBL807442 | 0.89 | ALDH1A1 (0.63) | ALDH1A1KDM4EPOLBTSHRSMN1; SMN2 | |
| SCHEMBL16225898 | 0.88 | SIGMAR1 (0.67) | ALDH1A1KDM4EPOLBTSHRSMN1; SMN2 | |
| SCHEMBL12120556 | 0.88 | ALDH1A1 (0.60) | ALDH1A1KDM4EPOLBTSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7405658 | 0.87 | ALDH1A1 (0.61) | ALDH1A1KDM4EPOLBTSHRSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL28443624 | 0.87 | ALDH1A1 (0.61) | ALDH1A1KDM4EPOLBTSHRSMN1; SMN2 | |
| SCHEMBL2925984 | 0.86 | KDM4E (0.57) | ALDH1A1KDM4EPOLBTSHRSMN1; SMN2 | |
| SCHEMBL18704978 | 0.85 | ALDH1A1 (0.57) | ALDH1A1KDM4EPOLBTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140335050-A1 | METHODS, COMPOSITIONS, AND KITS FOR THE TREATMENT OF CANCER | THE GENERAL HOSPITAL CORPORATION (US) | 2014-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140335050-A1 | METHODS, COMPOSITIONS, AND KITS FOR THE TREATMENT OF CANCER | IL2RA, CD74, IL2 | ALDH1A1 1004/4885KDM4E 4836/4885POLB 3364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.