Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 18/20 | 0.67 |
| ▸ | PARP3 | Q9Y6F1 | 11/20 | 0.59 |
| ▸ | PARP2 | Q9UGN5 | 7/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.37 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16227217 | 0.95 | PARP1 (0.67) | PARP1PARP3PARP2CYP1A1CYP2D6 | |
| SCHEMBL16227155 | 0.88 | PARP1 (0.61) | PARP1PARP3PARP2CYP1A1CYP2D6 | |
| SCHEMBL16227242 | 0.86 | PARP1 (0.64) | PARP1PARP3PARP2CYP1A1CYP2D6 | |
| SCHEMBL16227584 | 0.85 | PARP1 (0.63) | PARP1PARP3PARP2CYP1A1CYP2D6 | |
| SCHEMBL853576 | 0.84 | PARP1 (0.55) | PARP1PARP3PARP2CYP1A1CYP2D6 | |
| SCHEMBL15468106 | 0.84 | PARP1 (0.53) | PARP1PARP3PARP2CYP1A1CYP2D6 | |
| SCHEMBL16227250 | 0.83 | PARP1 (0.67) | PARP1PARP3PARP2CYP1A1CYP2D6 | |
| SCHEMBL16227005 | 0.83 | PARP1 (0.68) | PARP1PARP3PARP2 | |
| SCHEMBL14975987 | 0.83 | PARP1 (0.73) | PARP1PARP3PARP2MAPK1 | |
| SCHEMBL16227419 | 0.82 | PARP1 (0.52) | PARP1PARP3PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10189930-B2 | Polymeric photoinitiators | ALLNEX BELGIUM S.A. (BE) | 2019-01-29 | — | — | US | disclosed |
| EP-2804849-B1 | AMINO PHOTO-REACTIVE BINDER | ALLNEX Belgium SA (BE) | 2018-06-27 | — | — | EP | disclosed |
| US-10005717-B2 | Photo-reactive binder | ALLNEX BELGIUM S.A. (BE) | 2018-06-26 | — | — | US | disclosed |
| US-10000446-B2 | Amino photo-reactive binder | ALLNEX BELGIUM S.A. (BE) | 2018-06-19 | — | — | US | disclosed |
| EP-2788328-B1 | 3-PHENYL-ISOQUINOLIN-1(2H)-ONE DERIVATIVES AS PARP-1 INHIBITORS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2018-01-31 | — | — | EP | disclosed |
| EP-3024858-B1 | POLYMERIC PHOTOINITIATORS | ALLNEX Belgium SA (BE) | 2017-10-18 | — | — | EP | disclosed |
| US-9422243-B2 | 3-phenyl-isoquinolin-1(2H)-one derivatives as PARP-1 inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. a corporation (IT) | 2016-08-23 | — | — | US | disclosed |
| EP-2804914-B1 | PHOTO-REACTIVE BINDER | ALLNEX Belgium SA (BE) | 2016-07-20 | — | — | EP | disclosed |
| US-20160130380-A1 | POLYMERIC PHOTOINITIATORS | ALLNEX BELGIUM S.A. (BE) | 2016-05-12 | — | — | US | disclosed |
| US-20140335327-A1 | AMINO PHOTO-REACTIVE BINDER | ALLNEX BELGIUM S.A. (BE) | 2014-11-13 | — | — | US | disclosed |
| US-20140336192-A1 | 3-PHENYL-ISOQUINOLIN-1(2H)-ONE DERIVATIVES AS PARP-1 INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. a corporation | 2014-11-13 | — | — | US | disclosed |
| US-20140335326-A1 | PHOTO-REACTIVE BINDER | ALLNEX BELGIUM S.A. (BE) | 2014-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140335327-A1 | AMINO PHOTO-REACTIVE BINDER | ADGRE5, METTL14, CD79B | PARP1 1452/4885PARP3 2272/4885PARP2 2913/4885 |
| US-20140336192-A1 | 3-PHENYL-ISOQUINOLIN-1(2H)-ONE DERIVATIVES AS PARP-1 INHIBITORS | PARP1, PARP2, PARP11 | PARP1 1/4885PARP3 4/4885PARP2 2/4885 |
| US-10000446-B2 | Amino photo-reactive binder | ADGRE5, GP6, CD79B | PARP1 1411/4885PARP3 2256/4885PARP2 2889/4885 |
| US-10005717-B2 | Photo-reactive binder | CD79B, ADGRE5, GP6 | PARP1 1272/4885PARP3 1737/4885PARP2 2362/4885 |
| US-20140335326-A1 | PHOTO-REACTIVE BINDER | CD79B, ADGRE5, GP6 | PARP1 1272/4885PARP3 1737/4885PARP2 2362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.