SCHEMBL162267

SCHEMBL162267

CC(=O)OCCCc1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.47
NPC1 O15118 1/20 0.47
RECQL P46063 1/20 0.47
RAB9A P51151 1/20 0.47
RAD52 P43351 1/20 0.46
CYP2J2 P51589 1/20 0.45
ALDH1A1 P00352 4/20 0.45
FFAR1 O14842 1/20 0.43
KDM4E B2RXH2 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
CHRM5 P08912 2/20 0.43
CHRM1 P11229 2/20 0.43
CHRM3 P20309 2/20 0.43
TNKS2 Q9H2K2 1/20 0.43
CTSK P43235 1/20 0.42
MAPT P10636 1/20 0.42
APOBEC3A P31941 1/20 0.42
APOBEC3G Q9HC16 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14063399 1.00 LMNA (0.51) LMNASMN1; SMN2NPC1RECQLRAB9A
SCHEMBL13777821 0.91 RAD52 (0.48) SMN1; SMN2NPC1RAB9ARAD52ALDH1A1
SCHEMBL26295148 0.86 LMNA (0.47) LMNASMN1; SMN2NPC1RECQLRAB9A
SCHEMBL12925369 0.86 LMNA (0.47) LMNASMN1; SMN2NPC1RECQLRAB9A
SCHEMBL2602456 0.86 LMNA (0.47) LMNASMN1; SMN2NPC1RECQLRAB9A
SCHEMBL1051 0.85 LMNA (0.68) LMNASMN1; SMN2NPC1RECQLRAB9A
SCHEMBL279299 0.85 LMNA (0.49) LMNASMN1; SMN2NPC1RECQLRAB9A
SCHEMBL14448404 0.85 RAD52 (0.47) SMN1; SMN2RAD52ALDH1A1CHRM5CHRM1
SCHEMBL14063405 0.85 AKR1B10 (0.41) LMNASMN1; SMN2NPC1RECQLRAB9A
Hexane SCHEMBL28355428 0.83 LMNA (0.60) LMNASMN1; SMN2NPC1RECQLRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013148892-A1 BENZYLIDENE DERIVATIVE CHROMOPHORES FOR PHOTOREFRACTIVE COMPOSITIONS NITTO DENKO CORPORATION (JP) 2013-10-03 WO disclosed
EP-2616878-A1 PHOTOREFRACTIVE DEVICE CONTAINING A CHROMOPHORE-DOPED POLYMER LAYER AND ITS MANUFACTURING METHOD Nitto Denko Corporation (JP) 2013-07-24 EP disclosed
EP-2612198-A1 SYSTEMS AND METHODS FOR IMPROVING THE PERFORMANCE OF A PHOTOREFRACTIVE DEVICE BY UTILIZING ELECTROLYTES Nitto Denko Corporation (JP) 2013-07-10 EP disclosed
US-20130170016-A1 PHOTOREFRACTIVE DEVICE CONTAINING A CHROMOPHORE-DOPED POLYMER LAYER AND ITS MANUFACTURING METHOD NITTO DENKO CORPORATION (JP) 2013-07-04 US disclosed
US-20130163086-A1 SYSTEMS AND METHODS FOR IMPROVING THE PERFORMANCE OF A PHOTOREFRACTIVE DEVICE BY UTILIZING ELECTROLYTES NITTO DENKO CORPORATION (JP) 2013-06-27 US disclosed
EP-2434340-B1 Systems and methods for improving the performance of a photorefractive device NITTO DENKO CORP (JP) 2013-06-19 EP disclosed
WO-2013075050-A1 PHOTOREFRACTIVE DEVICE CONTAINING CARBON NANOTUBE-DOPED POLYMER LAYERS AND ITS MANUFACTURING METHOD NITTO DENKO CORPORATION (JP) 2013-05-23 WO disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-20120275007-A1 OPTICAL DEVICES FOR MODULATING LIGHT OF PHOTOREFRACTIVE COMPOSITIONS WITH THERMAL CONTROL NITTO DENKO CORPORATION (JP) 2012-11-01 US disclosed
EP-2049945-A2 NON-LINEAR OPTICAL DEVICE WITH LONG GRATING PERSISTENCY Nitto Denko Corporation (JP) 2009-04-22 EP disclosed
US-20090052009-A1 NON-LINEAR OPTICAL DEVICE SENSITIVE TO GREEN LASER NITTO DENKO CORPORATION (JP) 2009-02-26 US disclosed
US-20080220356-A1 Electrophotographic photoreceptor, process cartridge and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2008-09-11 US disclosed
US-20080220356-A1 Electrophotographic photoreceptor, process cartridge and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2008-09-11 US disclosed
US-20080039603-A1 NON-LINEAR OPTICAL DEVICE WITH LONG GRATING PERSISTENCY NITTO DENKO CORPORATION (JP) 2008-02-14 US disclosed
WO-2008013774-A2 NON-LINEAR OPTICAL DEVICE WITH LONG GRATING PERSISTENCY NITTO DENKO CORPORATION (JP) 2008-01-31 WO disclosed
WO-2008013775-A2 NON-LINEAR OPTICAL DEVICE SENSITIVE TO GREEN LASER NITTO DENKO CORPORATION (JP) 2008-01-31 WO disclosed
EP-1874891-A2 PHOTOREFRACTIVE COMPOSITION Nitto Denko Corporation (JP) 2008-01-09 EP disclosed
WO-2006112926-A2 PHOTOREFRACTIVE COMPOSITION NITTO DENKO CORPORATION (JP) 2006-10-26 WO disclosed
US-20060235163-A1 Photorefractive composition NITTO DENKO CORPORATION (JP) 2006-10-19 US disclosed