SCHEMBL16227464

SCHEMBL16227464

O=c1oc2ccccc2cc1CO[C@H]1[C@@H](O)[C@@H](CO)O[C@@H](S[C@@H]2O[C@H](CO)[C@H](O)[C@H](OCc3cc4ccccc4oc3=O)[C@H]2O)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 19/20 1.00
LGALS1 P09382 12/20 1.00
LGALS9 O00182 10/20 1.00
LGALS8 O00214 6/20 1.00
LGALS2 P05162 1/20 1.00
LGALS4 P56470 1/20 1.00
LGALS7; LGALS7B P47929 5/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15150623 1.00 LGALS3 (1.00) LGALS3LGALS1LGALS9LGALS8LGALS2
SCHEMBL16231583 1.00 LGALS3 (1.00) LGALS3LGALS1LGALS9LGALS8LGALS2
SCHEMBL16227328 0.89 LGALS3 (0.82) LGALS3LGALS1LGALS9LGALS8LGALS2
SCHEMBL16227420 0.89 LGALS3 (0.80) LGALS3LGALS1LGALS9LGALS8LGALS2
SCHEMBL16234129 0.89 LGALS3 (0.80) LGALS3LGALS1LGALS9LGALS8LGALS2
SCHEMBL16234124 0.89 LGALS3 (0.82) LGALS3LGALS1LGALS9LGALS8LGALS2
SCHEMBL16231585 0.89 LGALS3 (0.80) LGALS3LGALS1LGALS9LGALS8LGALS2
SCHEMBL16231584 0.89 LGALS3 (0.82) LGALS3LGALS1LGALS9LGALS8LGALS2
SCHEMBL16231590 0.88 LGALS3 (0.80) LGALS3LGALS1LGALS9LGALS8LGALS2
SCHEMBL16234114 0.88 LGALS3 (0.80) LGALS3LGALS1LGALS9LGALS8LGALS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9353141-B2 Galectoside inhibitors of galectins GALECTO BIOTECH AB (DK) 2016-05-31 US claimed
EP-2807176-B1 NOVEL GALACTOSIDE INHIBITORS OF GALECTINS GALECTO BIOTECH AB (DK) 2015-12-30 EP claimed
US-20140336146-A1 Novel galectoside inhibitors of galectins GALECTO BIOTECH AB (DK) 2014-11-13 US claimed
US-9353141-B2 Galectoside inhibitors of galectins GALECTO BIOTECH AB (DK) 2016-05-31 US disclosed
CN-104066743-B Novel galactoside inhibitors of galectins GALECTO BIOTECH AB (DK) 2016-04-06 CN disclosed
EP-2807176-B1 NOVEL GALACTOSIDE INHIBITORS OF GALECTINS GALECTO BIOTECH AB (DK) 2015-12-30 EP disclosed
US-20140336146-A1 Novel galectoside inhibitors of galectins GALECTO BIOTECH AB (DK) 2014-11-13 US disclosed
CN-104066743-A Novel galactoside inhibitors of galectins GALECTO BIOTECH AB 2014-09-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140336146-A1 Novel galectoside inhibitors of galectins LGALS3, LGALS1, LGALS3BP LGALS3 1/4885LGALS1 2/4885LGALS9 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.