Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 5/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12328159 | 0.99 | SCN10A (0.34) | SCN10ANR1H4CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL15373032 | 0.92 | SCN10A (0.32) | SCN10ANR1H4CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL15105935 | 0.92 | CHRNB2 (0.38) | SCN10ANR1H4CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL882749 | 0.92 | CHRNB2 (0.38) | SCN10ANR1H4CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL883089 | 0.92 | CHRNB2 (0.38) | SCN10ANR1H4CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL10177443 | 0.90 | CHRNB2 (0.39) | SCN10ANR1H4CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL1357749 | 0.89 | SCN10A (0.31) | SCN10A | |
| SCHEMBL1357750 | 0.89 | SCN10A (0.31) | SCN10A | |
| SCHEMBL12328015 | 0.85 | MKNK1 (0.30) | CHRNB2CHRNA7CHRNA4MKNK1 | |
| SCHEMBL1293343 | 0.85 | NR1H4 (0.44) | SCN10ANR1H4CHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414350-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2014-11-12 | — | — | EP | disclosed |