SCHEMBL16229872

SCHEMBL16229872

CCCCCc1ccc(-c2ccc(CCC)cc2)c(F)c1F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 9/20 0.46
HSD11B1 P28845 1/20 0.40
RARA P10276 2/20 0.40
RARG P13631 1/20 0.40
HSD17B10 Q99714 2/20 0.40
TSHR P16473 2/20 0.40
CHKA P35790 1/20 0.39
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 2/20 0.39
KMT2A Q03164 2/20 0.39
MPL P40238 2/20 0.39
MTOR P42345 1/20 0.39
ESR1 P03372 2/20 0.39
ADRA2A P08913 2/20 0.39
ADORA3 P0DMS8 2/20 0.39
TACR2 P21452 2/20 0.39
SLC6A2 P23975 2/20 0.39
SLC6A4 P31645 2/20 0.39
SLC6A3 Q01959 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9485527 0.98 RARB (0.45) RARBHSD11B1RARARARGHSD17B10
SCHEMBL9493798 0.98 RARB (0.45) RARBHSD11B1RARARARGHSD17B10
SCHEMBL9486681 0.97 RARB (0.47) RARBHSD11B1RARARARGHSD17B10
SCHEMBL9486110 0.97 RARB (0.47) RARBHSD11B1RARARARGHSD17B10
SCHEMBL2208150 0.97 RARB (0.47) RARBHSD11B1RARARARGHSD17B10
SCHEMBL12740085 0.97 RARB (0.44) RARBHSD11B1RARARARGHSD17B10
SCHEMBL9494394 0.97 RARB (0.47) RARBHSD11B1RARARARGHSD17B10
SCHEMBL9496056 0.97 RARB (0.47) RARBHSD11B1RARARARGHSD17B10
SCHEMBL9486821 0.97 RARB (0.47) RARBHSD11B1RARARARGHSD17B10
SCHEMBL9493581 0.97 RARB (0.47) RARBHSD11B1RARARARGHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-11466211-B2 Liquid crystal composition and liquid crystal display element including the same DIC CORPORATION (JP) 2022-10-11 US disclosed
US-11345857-B2 Spontaneous alignment assistant for liquid crystal compositions DIC CORPORATION (JP) 2022-05-31 US disclosed
EP-2907864-B2 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THIS COMPOSITION DAINIPPON INK & CHEMICALS (JP) 2022-05-18 EP disclosed
US-11326103-B2 Liquid crystal display device DIC CORPORATION (JP) 2022-05-10 US disclosed
US-20220128867-A1 SUBSTRATE AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2022-04-28 US disclosed
US-11312906-B2 Polymerizable monomer, liquid crystal composition using polymerizable monomer, and liquid crystal display device DIC CORPORATION (JP) 2022-04-26 US disclosed
US-20160060522-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-03-03 US disclosed
US-20160060521-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2016-03-03 US disclosed
US-20160060522-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-03-03 US disclosed
US-20160017227-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT INCLUDING THE SAME DIC CORPORATION (JP) 2016-01-21 US disclosed
US-20160017227-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT INCLUDING THE SAME DIC CORPORATION (JP) 2016-01-21 US disclosed
US-20150197691-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2015-07-16 US disclosed
US-20150197691-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2015-07-16 US disclosed
EP-2884335-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC Corporation (JP) 2015-06-17 EP disclosed
EP-2884334-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC Corporation (JP) 2015-06-17 EP disclosed
EP-2801600-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT INCORPORATING SAME DIC Corporation (JP) 2014-11-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11345857-B2 Spontaneous alignment assistant for liquid crystal compositions VAC14, VAPA, SFN RARB 3761/4885HSD11B1 3498/4885RARA 1982/4885
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound OCIAD2, PKN2, SKP1 RARB 3196/4885HSD11B1 1275/4885RARA 3675/4885
US-20150197691-A1 LIQUID CRYSTAL DISPLAY DEVICE CFL1, FMNL1, EFHD2 RARB 4417/4885HSD11B1 643/4885RARA 4309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.