SCHEMBL16229873

SCHEMBL16229873

CCCCCc1ccc(-c2ccc(CCC)c(F)c2F)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 9/20 0.49
HSD11B1 P28845 3/20 0.43
HSD17B10 Q99714 2/20 0.43
TSHR P16473 1/20 0.43
RARA P10276 2/20 0.43
RARG P13631 1/20 0.43
ESR1 P03372 2/20 0.42
ADRA2A P08913 2/20 0.42
ADORA3 P0DMS8 2/20 0.42
TACR2 P21452 2/20 0.42
SLC6A2 P23975 2/20 0.42
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
ALDH1A1 P00352 2/20 0.42
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
SHBG P04278 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
HSPD1 P10809 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9496950 0.98 RARB (0.48) RARBHSD11B1HSD17B10TSHRRARA
SCHEMBL9486012 0.98 RARB (0.48) RARBHSD11B1HSD17B10TSHRRARA
SCHEMBL9495430 0.97 RARB (0.50) RARBHSD11B1HSD17B10TSHRRARA
SCHEMBL9494190 0.97 RARB (0.50) RARBHSD11B1HSD17B10TSHRRARA
SCHEMBL9493602 0.97 RARB (0.50) RARBHSD11B1HSD17B10TSHRRARA
SCHEMBL9494840 0.97 RARB (0.50) RARBHSD11B1HSD17B10TSHRRARA
SCHEMBL9493102 0.97 RARB (0.50) RARBHSD11B1HSD17B10TSHRRARA
SCHEMBL9493556 0.97 RARB (0.50) RARBHSD11B1HSD17B10TSHRRARA
SCHEMBL9563854 0.95 RARB (0.50) RARBHSD11B1HSD17B10TSHRRARA
SCHEMBL20346176 0.95 MPL (0.44) RARBHSD11B1HSD17B10RARARARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-11466211-B2 Liquid crystal composition and liquid crystal display element including the same DIC CORPORATION (JP) 2022-10-11 US disclosed
US-11345857-B2 Spontaneous alignment assistant for liquid crystal compositions DIC CORPORATION (JP) 2022-05-31 US disclosed
EP-2907864-B2 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THIS COMPOSITION DAINIPPON INK & CHEMICALS (JP) 2022-05-18 EP disclosed
US-11326103-B2 Liquid crystal display device DIC CORPORATION (JP) 2022-05-10 US disclosed
US-20220128867-A1 SUBSTRATE AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2022-04-28 US disclosed
US-11312906-B2 Polymerizable monomer, liquid crystal composition using polymerizable monomer, and liquid crystal display device DIC CORPORATION (JP) 2022-04-26 US disclosed
US-20150376500-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME DIC CORPORATION (JP) 2015-12-31 US disclosed
US-9139777-B2 Composition of liquid crystal medium SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD (CN) 2015-09-22 US disclosed
US-20150197691-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2015-07-16 US disclosed
US-20150197691-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2015-07-16 US disclosed
EP-2884334-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC Corporation (JP) 2015-06-17 EP disclosed
EP-2884335-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC Corporation (JP) 2015-06-17 EP disclosed
EP-2883937-A1 LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC Corporation (JP) 2015-06-17 EP disclosed
EP-2883938-A1 LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT, AND LIQUID CRYSTAL DISPLAY DIC Corporation (JP) 2015-06-17 EP disclosed
EP-2806009-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT INCORPORATING SAME DIC Corporation (JP) 2014-11-26 EP disclosed
EP-2801600-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT INCORPORATING SAME DIC Corporation (JP) 2014-11-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11345857-B2 Spontaneous alignment assistant for liquid crystal compositions VAC14, VAPA, SFN RARB 3761/4885HSD11B1 3498/4885HSD17B10 2613/4885
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound OCIAD2, PKN2, SKP1 RARB 3196/4885HSD11B1 1275/4885HSD17B10 2195/4885
US-20150197691-A1 LIQUID CRYSTAL DISPLAY DEVICE CFL1, FMNL1, EFHD2 RARB 4417/4885HSD11B1 643/4885HSD17B10 1813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.