SCHEMBL1622995

SCHEMBL1622995

C[SiH](C)[Hf](C)(C)C1C=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.33
HTR6 P50406 1/20 0.33
SIGMAR1 Q99720 4/20 0.31
KDM4E B2RXH2 2/20 0.31
BRD4 O60885 1/20 0.31
CCL2 P13500 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CHRM2 P08172 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD2 P14416 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
NFKB1 P19838 1/20 0.31
CHRM3 P20309 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9579051 0.83 HTR2A (0.35) HTR2AHTR6SIGMAR1KDM4EBRD4
Hydrochloric Acid SCHEMBL8160816 0.81 KDM4E (0.37) HTR2AHTR6SIGMAR1KDM4EBRD4
Hydrochloric Acid SCHEMBL8160808 0.81 KDM4E (0.37) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL28290857 0.80 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL8380950 0.80 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL15189742 0.79 HTR2A (0.36) HTR2AHTR6SIGMAR1KDM4EBRD4
Ethylene SCHEMBL4337188 0.77 HTR2A (0.35) HTR2AHTR6SIGMAR1KDM4EBRD4
Hydrochloric Acid SCHEMBL7715911 0.76 KDM4E (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL7066600 0.75 GPR3 (0.31) HTR2AKDM4ELMNATP53CHRM2
SCHEMBL7599530 0.74 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10927207-B2 Thermoplastic vulcanizate compositions EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-02-23 US disclosed
EP-3775003-A1 THEMOPLASTIC VULCANIZATE COMPOSITIONS ExxonMobil Chemical Patents Inc. (US) 2021-02-17 EP disclosed
US-20190309153-A1 Thermoplastic Vulcanizate Compositions CELANESE INTERNATIONAL CORPORATION 2019-10-10 US disclosed
WO-2019194961-A1 THEMOPLASTIC VULCANIZATE COMPOSITIONS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-10-10 WO disclosed
EP-1687345-B1 TRANSPARENT AND TRANSLUCENT CROSSLINKED PROPYLENEBASED ELASTOMERS, AND THEIR PRODUCTION AND USE EXXONMOBIL CHEM PATENTS INC (US) 2013-12-25 EP disclosed
US-8202467-B2 Propylene-based polymer article EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-06-19 US disclosed
US-8013093-B2 Containing ethylene and optionally a diene which have isotactic polypropylene crystallinity, and specified melting point and heat of fusion and partially cured by radiation or peroxide; extrusion; fabrics, films; retain desirable elasticity characteristics after dyeing and/or heat-setting EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-09-06 US disclosed
US-7928165-B2 Improved tensile strength and tear strength compared to commercially available EPDM terpolymers (EPDM, ethylene-propylene-diene); specified isotactic propylene triad tacticity, melting point and heat of fusion; moldings and extruded articles EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-04-19 US disclosed
US-7803876-B2 Processes for producing polymer blends and polymer blend pellets EXXONMOBIL CHEMICAL PATENT INC. (US) 2010-09-28 US disclosed
US-7655730-B2 blend of polypropylene as first polymeric component , ethylene propylene copolymer as second polymeric component, and a hydrocarbon resin such as hydrogenated polydicyclopentadiene, hydrogenated rosins; polyterpene resins; elasticity, softness, flexibility; molecular weight distribution EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-02-02 US disclosed
EP-1687345-A1 TRANSPARENT AND TRANSLUCENT CROSSLINKED PROPYLENEBASED ELASTOMERS, AND THEIR PRODUCTION AND USE Exxonmobil Chemical Patents Inc. (US) 2006-08-09 EP disclosed
EP-1687346-A1 PROPYLENE-BASED ELASTOMERS AND USES THEREOF Exxonmobil Chemical Patents Inc. (US) 2006-08-09 EP disclosed
US-20060170137-A1 Processes for producing polymer blends and polymer blend pellets EXXONMOBIL CHEMICAL PATENTS INC. 2006-08-03 US disclosed
US-20050131142-A1 High strength propylene-based elastomers and uses thereof EXXONMOBIL CHEMICAL PATENTS INC. 2005-06-16 US disclosed
WO-2005049672-A1 TRANSPARENT AND TRANSLUCENT CROSSLINKED PROPYLENEBASED ELASTOMERS, AND THEIR PRODUCTION AND USE EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-06-02 WO disclosed
WO-2005049670-A1 PROPYLENE-BASED ELASTOMERS AND USES THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-06-02 WO disclosed
WO-2005049671-A1 HIGH STRENGTH PROPYLENE-BASED ELASTOMERS AND USES THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-06-02 WO disclosed
US-20050107530-A1 Transparent and translucent crosslinked propylene-based elastomers, and their production and use EXXONMOBIL CHEMICAL PATENTS INC. 2005-05-19 US disclosed
US-20050107534-A1 Propylene-based elastomers and uses thereof EXXONMOBIL CHEMICAL PATENTS INC. 2005-05-19 US disclosed
US-20050107529-A1 Articles comprising propylene-based elastomers EXXONMOBIL CHEMICAL PATENTS INC. 2005-05-19 US disclosed