Ethylene

Ethylene

SCHEMBL4337188

C=C.C[Hf](C)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.35
HTR6 P50406 1/20 0.35
SIGMAR1 Q99720 6/20 0.33
KDM4E B2RXH2 2/20 0.33
BRD4 O60885 1/20 0.33
CCL2 P13500 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
CHRM2 P08172 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD2 P14416 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
NFKB1 P19838 1/20 0.33
CHRM3 P20309 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28290857 0.96 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL15189742 0.94 HTR2A (0.36) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL8380950 0.83 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
Ethylene SCHEMBL9289285 0.80 HTR6 (0.39) HTR2AHTR6
Ethylene SCHEMBL4323027 0.79 HTR2A (0.36) HTR2AHTR6SIGMAR1KDM4EBRD4
Hydrochloric Acid SCHEMBL7715911 0.78 KDM4E (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL23211989 0.78 NPC1 (0.30) LMNA
SCHEMBL1622995 0.77 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
Ethylene SCHEMBL4332388 0.77 HTR6 (0.33) HTR2AHTR6SIGMAR1
SCHEMBL7599530 0.77 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7592403-B2 Ethylene polymer, preparation process thereof and molded articles of the same MITSUI CHEMICALS, INC. (JP) 2009-09-22 US claimed
US-7592403-B2 Ethylene polymer, preparation process thereof and molded articles of the same MITSUI CHEMICALS, INC. (JP) 2009-09-22 US disclosed
US-20050267273-A1 Ethylene polymer, preparation process thereof and molded articles of the same MITSUI CHEMICALS, INC. 2005-12-01 US disclosed
EP-1231229-A2 Ethylene polymer, preparation process thereof and molded articles of the same Mitsui Chemicals, Inc. (JP) 2002-08-14 EP disclosed
US-20020107343-A1 Ethylene polymer, preparation process thereof and molded articles of the same MITSUI CHEMICALS, INC. 2002-08-08 US disclosed