Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868650 | 0.86 | FFAR1 (0.65) | FFAR1LPAR2HTR2CHTR2ASLC6A4 | |
| SCHEMBL21501054 | 0.86 | FFAR1 (0.65) | FFAR1LPAR2HTR2CHTR2ASLC6A4 | |
| SCHEMBL23116570 | 0.86 | FFAR1 (0.65) | FFAR1LPAR2HTR2CHTR2ASLC6A4 | |
| SCHEMBL10288305 | 0.86 | FFAR1 (0.65) | FFAR1LPAR2HTR2CHTR2ASLC6A4 | |
| SCHEMBL3042239 | 0.86 | FFAR1 (0.65) | FFAR1LPAR2HTR2CHTR2ASLC6A4 | |
| SCHEMBL29303274 | 0.85 | HTR2A (0.51) | FFAR1LPAR2HTR2CHTR2ASLC6A4 | |
| SCHEMBL29136846 | 0.81 | SLC9A1 (0.66) | HTR2CHTR2AHTR2BSLC6A3SLC9A1 | |
| SCHEMBL29830097 | 0.81 | SLC9A1 (0.66) | HTR2CHTR2AHTR2BSLC6A3SLC9A1 | |
| SCHEMBL29136847 | 0.81 | SLC9A1 (0.66) | HTR2CHTR2AHTR2BSLC6A3SLC9A1 | |
| SCHEMBL24737783 | 0.81 | SLC9A1 (0.66) | HTR2CHTR2AHTR2BSLC6A3SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140336198-A1 | Amine Derivatives as Potassium Channel Blockers | MERCK PATENT GMBH (DE) | 2014-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336198-A1 | Amine Derivatives as Potassium Channel Blockers | KCNA3, KCNH3, KCNK3 | FFAR1 2942/4885LPAR2 1257/4885HTR2C 2143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.