Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555382 | 1.00 | MAPT (0.52) | MAPTTSHRKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL11603537 | 0.98 | MAPT (0.50) | MAPTTSHRKDM4EALDH1A1HPGD | |
| SCHEMBL20581696 | 0.98 | MAPT (0.50) | MAPTTSHRKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL393289 | 0.98 | MAPT (0.50) | MAPTTSHRKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL27504813 | 0.98 | MAPT (0.50) | MAPTTSHRKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL27779824 | 0.98 | MAPT (0.50) | MAPTTSHRKDM4EALDH1A1HPGD | |
| Dimethylamine SCHEMBL27639205 | 0.94 | MAPT (0.47) | MAPTTSHRKDM4EALDH1A1HPGD | |
| SCHEMBL28203375 | 0.90 | KDM4E (0.44) | MAPTTSHRKDM4EALDH1A1HPGD | |
| Diethylamine SCHEMBL7576781 | 0.89 | MAPT (0.42) | MAPTTSHRKDM4EALDH1A1HPGD | |
| Fluorobenzene SCHEMBL28219883 | 0.89 | AGTR1 (0.44) | MAPTTSHRKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 842 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12617798-B2 | Imidazopyrazne derivatives | HOFFMANN-LA ROCHE INC. (US) | 2026-05-05 | — | — | US | claimed |
| WO-2024261504-A1 | BENZOFURAN-3-CARBOXYLIC ACID AMIDES AND BENZOFURAN-3- CARBONYL-BENZAMIDES, METHOD FOR THEIR PRODUCTION WITH HIGH SELECTIVITY, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PÉCSI TUDOMÁNYEGYETEM (HU) | 2024-12-26 | — | — | WO | claimed |
| CN-112004813-B | Oxadiazole compounds for controlling phytopathogenic fungi | PI工业有限公司 | 2024-03-29 | — | — | CN | claimed |
| EP-3310822-B1 | PROCATALYST FOR POLYMERIZATION OF OLEFINS COMPRISING AN AMINOBENZOATE INTERNAL DONOR AND A 1,3-DIETHER INTERNAL DONOR IN A SPECIFIC RATIO | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2023-10-11 | — | — | EP | claimed |
| US-20230212157-A1 | PYRAZOLE DERIVATIVES FOR THE TREATMENT OF CYSTIC FIBROSIS | ISTITUTO GIANNINA GASLINI (IT) | 2023-07-06 | — | — | US | claimed |
| WO-2023103261-A1 | CRYSTAL FORM B OF ETHYL 2-CYANO-3-AMINO-3-PHENYLACRYLATE, PREPARATION METHOD, AND APPLICATION | 江苏省农药研究所股份有限公司 | 2023-06-15 | — | — | WO | claimed |
| CN-108658816-B | N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides | 拜尔农作物科学股份公司 | 2023-05-02 | — | — | CN | claimed |
| US-11597723-B2 | Pyrazole derivatives for the treatment of cystic fibrosis | FONDAZIONE ISTITUTO ITALIANO DI TECHNOLOGIA (IT) | 2023-03-07 | — | — | US | claimed |
| CN-112294816-B | Application of ethyl benzamide compound in preparation of local anesthetic | 四川大学华西医院 | 2021-07-30 | — | — | CN | claimed |
| CN-112294816-A | Application of ethyl benzamide compound in preparation of local anesthetic | 四川大学华西医院 | 2021-02-02 | — | — | CN | claimed |
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | claimed |
| WO-2004072046-A2 | QUINOLINE DERIVATIVES AND THEIR USE FOR MODULATION OF LXR ACTIVITY | CAREX S.A. (FR) | 2004-08-26 | — | — | WO | claimed |
| EP-1392655-A2 | POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2004-03-03 | — | — | EP | claimed |
| WO-2003087071-A1 | SULFONAMIDE DERIVATIVES | CELLTECH R & D LIMITED (GB) | 2003-10-23 | — | — | WO | claimed |
| WO-2002062762-A2 | POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2002-08-15 | — | — | WO | claimed |
| US-6380247-B2 | A WOOD PRESERVATIVE; POTENTIATION WHEN MIXED WITH AT LEAST ONE OF 3-BROMO-2,3-DIIODO-2-PROPENYL-ETHYLCARBAMATE, 3-IODO-2-PROPYNYLBUTYL-CARBAMATE AND 4-CHLOROPHENYL-3-IODOPROPARGYLFORMAL; MICROBIOCIDES | SANKYO COMPANY, LIMITED (JP) | 2002-04-30 | — | — | US | claimed |
| EP-1150565-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION bioscience AG (DE) | 2001-11-07 | — | — | EP | claimed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | claimed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | claimed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212157-A1 | PYRAZOLE DERIVATIVES FOR THE TREATMENT OF CYSTIC FIBROSIS | CFTR, ABCC5, ABCC1 | MAPT 4663/4885TSHR 3655/4885KDM4E 4688/4885 |
| US-12617798-B2 | Imidazopyrazne derivatives | CLIC1, HCFC1, CXCR1 | MAPT 4861/4885TSHR 1079/4885KDM4E 3034/4885 |
| US-11597723-B2 | Pyrazole derivatives for the treatment of cystic fibrosis | CFTR, ABCC5, ABCC3 | MAPT 4662/4885TSHR 3688/4885KDM4E 4681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.