Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A9 | P06702 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.30 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16235463 | 0.88 | S100A9 (0.48) | S100A9MAP4K4MINK1TNIK | |
| SCHEMBL16235260 | 0.84 | S100A9 (0.37) | S100A9 | |
| SCHEMBL16235234 | 0.83 | FLT1 (0.38) | ALDH1A1MAPTKDM4EPTGDR2 | |
| SCHEMBL16235114 | 0.79 | ALDH1A1 (0.30) | ALDH1A1POLB | |
| SCHEMBL16235648 | 0.73 | S100A9 (0.33) | S100A9 | |
| SCHEMBL16235296 | 0.71 | S100A9 (0.31) | S100A9 | |
| SCHEMBL16235658 | 0.71 | — | — | |
| SCHEMBL16235728 | 0.69 | ATF1 (0.39) | S100A9ALDH1A1 | |
| SCHEMBL16235266 | 0.69 | MAPT (0.38) | ALDH1A1MAPTKDM4E | |
| SCHEMBL16235667 | 0.69 | CA2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925743-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | Active Biotech AB (SE) | 2015-10-07 | — | — | EP | claimed |
| WO-2014184234-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | ACTIVE BIOTECH AB (SE) | 2014-11-20 | — | — | WO | claimed |