Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30305109 | 0.85 | GABRA1 (0.56) | ALDH1A1LMNAL3MBTL1MAPTGAA | |
| SCHEMBL2311400 | 0.85 | GABRA1 (0.56) | ALDH1A1LMNAL3MBTL1MAPTGAA | |
| SCHEMBL2312725 | 0.85 | ALDH1A1 (0.55) | ALDH1A1LMNAL3MBTL1MAPTGAA | |
| SCHEMBL1372751 | 0.83 | ALDH1A1 (0.59) | ALDH1A1LMNAL3MBTL1MAPTGAA | |
| SCHEMBL30086907 | 0.83 | ALDH1A1 (0.59) | ALDH1A1LMNAL3MBTL1MAPTGAA | |
| SCHEMBL26617566 | 0.82 | KDM4E (0.53) | ALDH1A1LMNAL3MBTL1MAPTGAA | |
| SCHEMBL30681975 | 0.82 | KDM4E (0.53) | ALDH1A1LMNAL3MBTL1MAPTGAA | |
| SCHEMBL829213 | 0.81 | KDM4E (0.76) | ALDH1A1LMNAL3MBTL1MAPTGAA | |
| SCHEMBL7431714 | 0.80 | MEN1 (0.63) | MAOBALDH1A1MAPTGAAKDM4E | |
| SCHEMBL31345632 | 0.79 | ALDH1A1 (0.57) | ALDH1A1LMNAL3MBTL1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2996691-A1 | COMPOUNDS FOR INHIBITING DRUG-RESISTANT STRAINS OF HIV-1 INTEGRASE | The U.S.A. as represented by the Secretary, Department of Health and Human Services (US) | 2016-03-23 | — | — | EP | disclosed |
| WO-2014186398-A1 | COMPOUNDS FOR INHIBITING DRUG-RESISTANT STRAINS OF HIV-1 INTEGRASE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2014-11-20 | — | — | WO | disclosed |