Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NCEH1 | Q6PIU2 | 8/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16236445 | 0.91 | LMNA (0.74) | LMNASMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL16237079 | 0.86 | LMNA (0.67) | LMNASMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL16237227 | 0.86 | LMNA (0.67) | LMNASMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL16237183 | 0.85 | LMNA (0.66) | LMNASMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL16236775 | 0.84 | TYMS (0.47) | SMN1; SMN2NPC1MAPTRAB9AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL16236295 | 0.84 | LMNA (0.64) | LMNASMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL16236870 | 0.82 | LMNA (0.63) | LMNASMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL16236701 | 0.82 | LMNA (0.63) | LMNASMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL17113691 | 0.82 | HSD17B10 (0.61) | LMNASMN1; SMN2NPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL16236429 | 0.81 | LMNA (0.62) | LMNASMN1; SMN2NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997050-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2018-01-17 | — | — | EP | disclosed |
| US-9714303-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2017-07-25 | — | — | US | disclosed |
| US-20160115261-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia, s.r.l. (IT) | 2016-04-28 | — | — | US | disclosed |
| EP-2997050-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2016-03-23 | — | — | EP | disclosed |
| WO-2014184171-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2014-11-20 | — | — | WO | disclosed |
| EP-2803678-A1 | Catalyst components for the polymerization of olefins | Basell Poliolefine Italia S.r.l. (IT) | 2014-11-19 | — | — | EP | disclosed |