SCHEMBL16237183

SCHEMBL16237183

CCN(CC)C(=O)Oc1ccc2ccccc2c1-c1c(O)ccc2ccccc12

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.66
SMN1; SMN2 Q16637 2/20 0.66
MAPT P10636 2/20 0.66
NPC1 O15118 1/20 0.66
RAB9A P51151 1/20 0.66
L3MBTL1 Q9Y468 1/20 0.54
TSHR P16473 1/20 0.54
NCEH1 Q6PIU2 8/20 0.50
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
HSD17B10 Q99714 1/20 0.46
KDM4E B2RXH2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16236445 0.93 LMNA (0.74) LMNASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL16237227 0.88 LMNA (0.67) LMNASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL16237079 0.88 LMNA (0.67) LMNASMN1; SMN2MAPTNPC1RAB9A
Hydrochloric Acid SCHEMBL16236295 0.86 LMNA (0.64) LMNASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL16236129 0.85 LMNA (0.63) LMNASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL16236870 0.85 LMNA (0.63) LMNASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL16236701 0.85 LMNA (0.63) LMNASMN1; SMN2MAPTNPC1RAB9A
Hydrochloric Acid SCHEMBL16236429 0.84 LMNA (0.62) LMNASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL16236469 0.83 LMNA (0.60) LMNASMN1; SMN2MAPTNPC1RAB9A
SCHEMBL16964922 0.81 LMNA (0.72) LMNASMN1; SMN2MAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2997050-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2018-01-17 EP disclosed
US-9714303-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2017-07-25 US disclosed
US-20160115261-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia, s.r.l. (IT) 2016-04-28 US disclosed
EP-2997050-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2016-03-23 EP disclosed
WO-2014184171-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2014-11-20 WO disclosed
EP-2803678-A1 Catalyst components for the polymerization of olefins Basell Poliolefine Italia S.r.l. (IT) 2014-11-19 EP disclosed