Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | ESR1 | P03372 | 5/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | JAK2 | O60674 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | TOP1 | P11387 | 1/20 | 0.54 |
| ▸ | FABP7 | O15540 | 1/20 | 0.52 |
| ▸ | FABP3 | P05413 | 1/20 | 0.52 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.52 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30486015 | 1.00 | KMT2A (0.63) | KMT2AESR1ESR2MAPTHSD17B10 | |
| SCHEMBL31517375 | 0.91 | KMT2A (0.68) | KMT2AESR1ESR2MAPTHSD17B10 | |
| SCHEMBL22353263 | 0.87 | SLC6A3 (0.58) | KMT2AESR1ESR2MAPTHSD17B10 | |
| SCHEMBL1918507 | 0.85 | KMT2A (0.71) | KMT2AESR1ESR2MAPTHSD17B10 | |
| SCHEMBL3309694 | 0.83 | FABP7 (0.56) | KMT2AESR1ESR2MAPTHSD17B10 | |
| SCHEMBL28822923 | 0.83 | KMT2A (0.69) | KMT2AESR1ESR2MAPTHSD17B10 | |
| SCHEMBL22090951 | 0.83 | KMT2A (0.56) | KMT2AESR1ESR2MAPTHSD17B10 | |
| SCHEMBL16236368 | 0.82 | SLC6A3 (0.65) | KMT2AESR1ESR2MAPTHSD17B10 | |
| SCHEMBL17698877 | 0.82 | KMT2A (0.49) | KMT2AESR1ESR2MAPTHSD17B10 | |
| SCHEMBL844563 | 0.81 | ESR1 (0.72) | KMT2AESR1ESR2MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997050-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2018-01-17 | — | — | EP | disclosed |
| US-9714303-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2017-07-25 | — | — | US | disclosed |
| US-20160115261-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia, s.r.l. (IT) | 2016-04-28 | — | — | US | disclosed |
| EP-2997050-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2016-03-23 | — | — | EP | disclosed |
| WO-2014184171-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2014-11-20 | — | — | WO | disclosed |
| EP-2803678-A1 | Catalyst components for the polymerization of olefins | Basell Poliolefine Italia S.r.l. (IT) | 2014-11-19 | — | — | EP | disclosed |