SCHEMBL22353263

SCHEMBL22353263

COC(=O)c1ccc(C(=O)Oc2ccccc2-c2ccccc2O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.58
MAPT P10636 4/20 0.50
ESR1 P03372 4/20 0.50
ESR2 Q92731 4/20 0.50
TSHR P16473 2/20 0.50
PRSS1 P07477 1/20 0.50
ACR P10323 1/20 0.50
KDM4A O75164 1/20 0.50
KMT2A Q03164 4/20 0.49
MEN1 O00255 2/20 0.49
NPSR1 Q6W5P4 2/20 0.49
EGFR P00533 1/20 0.49
JAK2 O60674 1/20 0.49
USP2 O75604 1/20 0.49
GAA P10253 1/20 0.49
ALOX15 P16050 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
HSD17B10 Q99714 1/20 0.49
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30486015 0.87 KMT2A (0.63) SLC6A3MAPTESR1ESR2KMT2A
SCHEMBL16236385 0.87 KMT2A (0.63) SLC6A3MAPTESR1ESR2KMT2A
SCHEMBL17698877 0.82 KMT2A (0.49) SLC6A3MAPTESR1ESR2PRSS1
SCHEMBL4391264 0.81 KMT2A (0.47) SLC6A3MAPTPRSS1ACRKDM4A
SCHEMBL2035147 0.80 EGFR (0.71) SLC6A3MAPTTSHRKDM4AKMT2A
SCHEMBL5706076 0.80 SLC6A3 (0.87) SLC6A3MAPTTSHRPRSS1ACR
SCHEMBL6813193 0.78 SLC6A3 (0.90) SLC6A3MAPTTSHRPRSS1ACR
SCHEMBL16838267 0.78 MAPT (0.72) SLC6A3MAPTTSHRPRSS1ACR
SCHEMBL22090012 0.78 MAPT (0.47) MAPTESR1ESR2TSHRKMT2A
SCHEMBL688142 0.77 ESR1 (0.62) SLC6A3MAPTESR1ESR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11174343-B2 Bioderived biphenyl-containing compounds and their conversion to polymers and macromonomers ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2021-11-16 US disclosed
US-20200262972-A1 BIODERIVED BIPHENYL-CONTAINING COMPOUNDS AND THEIR CONVERSION TO POLYMERS AND MACROMONOMERS Alliance for Energy Innovation, LLC 2020-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200262972-A1 BIODERIVED BIPHENYL-CONTAINING COMPOUNDS AND THEIR CONVERSION TO POLYMERS AND MACROMONOMERS CYP1B1, PHB2, PCBP1 SLC6A3 4730/4885MAPT 4073/4885ESR1 205/4885
US-11174343-B2 Bioderived biphenyl-containing compounds and their conversion to polymers and macromonomers CYP1B1, PHB2, PCBP1 SLC6A3 4730/4885MAPT 4073/4885ESR1 205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.