Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrole SCHEMBL28720425 | 0.80 | MAOA (0.62) | MAOAMAP4K4MEN1PSIP1AXL | |
| SCHEMBL1829400 | 0.79 | — | — | |
| SCHEMBL30500254 | 0.79 | MAOA (0.83) | MAOAMAP4K4MEN1PSIP1AXL | |
| SCHEMBL29403794 | 0.79 | MAOA (0.83) | MAOAMAP4K4MEN1PSIP1AXL | |
| SCHEMBL251095 | 0.79 | MAOA (0.83) | MAOAMAP4K4MEN1PSIP1AXL | |
| Hydrochloric Acid SCHEMBL5679694 | 0.77 | CYP1A2 (0.44) | CYP3A4 | |
| SCHEMBL30935373 | 0.77 | CYP1A2 (0.44) | CYP3A4 | |
| SCHEMBL11388729 | 0.77 | MAOA (0.79) | MAOAMAP4K4MEN1PSIP1AXL | |
| SCHEMBL310174 | 0.77 | MAOA (0.79) | MAOAMAP4K4MEN1PSIP1AXL | |
| Ammonia Solution, Strong SCHEMBL21296174 | 0.77 | MAOA (0.79) | MAOAMAP4K4MEN1PSIP1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4389738-A1 | SOS1 INHIBITOR AND USE THEREOF | Kanaph Therapeutics Inc. (KR) | 2024-06-26 | — | — | EP | disclosed |
| US-20160122187-A1 | Process for Covalently Grafting a Carbonaceous Material | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2016-05-05 | — | — | US | disclosed |
| EP-2997092-A1 | PROCESS FOR COVALENTLY GRAFTING A CARBONACEOUS MATERIAL | Total Research & Technology Feluy (BE) | 2016-03-23 | — | — | EP | disclosed |
| WO-2014184330-A1 | PROCESS FOR COVALENTLY GRAFTING A CARBONACEOUS MATERIAL | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2014-11-20 | — | — | WO | disclosed |