SCHEMBL251095

SCHEMBL251095

Nc1cccc(-c2cccc(N)c2)c1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.83
CYP3A4 P08684 2/20 0.69
CASP1 P29466 1/20 0.69
RECQL P46063 1/20 0.69
MAP4K4 O95819 5/20 0.65
MEN1 O00255 2/20 0.62
PSIP1 O75475 1/20 0.62
AXL P30530 1/20 0.62
MKNK1 Q9BUB5 1/20 0.62
MKNK2 Q9HBH9 1/20 0.62
CA12 O43570 2/20 0.58
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
CA9 Q16790 2/20 0.58
ALDH1A1 P00352 3/20 0.52
CA7 P43166 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
CA14 Q9ULX7 1/20 0.52
MECP2 P51608 1/20 0.52
KDM4E B2RXH2 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29403794 1.00 MAOA (0.83) MAOACYP3A4CASP1RECQLMAP4K4
SCHEMBL30500254 1.00 MAOA (0.83) MAOACYP3A4CASP1RECQLMAP4K4
Water SCHEMBL2444002 0.97 MAOA (0.79) MAOACYP3A4CASP1RECQLMAP4K4
Methane SCHEMBL21853746 0.97 MAOA (0.79) MAOACYP3A4CASP1RECQLMAP4K4
SCHEMBL310174 0.97 MAOA (0.79) MAOACYP3A4CASP1RECQLMAP4K4
SCHEMBL11388729 0.97 MAOA (0.79) MAOACYP3A4CASP1RECQLMAP4K4
Water SCHEMBL3862803 0.97 MAOA (0.79) MAOACYP3A4CASP1RECQLMAP4K4
Ammonia Solution, Strong SCHEMBL21296174 0.97 MAOA (0.79) MAOACYP3A4CASP1RECQLMAP4K4
SCHEMBL31131352 0.97 MAOA (0.79) MAOACYP3A4CASP1RECQLMAP4K4
Hydrogen Sulfide SCHEMBL28624863 0.97 MAOA (0.79) MAOACYP3A4CASP1RECQLMAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1615 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015454-A1 HIGH PERFORMANCE, AMBIENT CURE POLYURETHANES COMPRISING POLYCAPROLACTONE POLYOLS INGEVITY UK LTD (GB) 2026-01-15 US claimed
EP-4594381-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE Ingevity UK Ltd (GB) 2025-08-06 EP claimed
US-20250243313-A1 POLYCAPROLACTONE POLYOLS, ELASTOMERS, AND METHODS OF MAKING AND USING THE SAME INGEVITY UK LTD (GB) 2025-07-31 US claimed
US-20250230274-A1 POLYCAPROLACTONE POLYOLS, POLYURETHANE DISPERSIONS, AND METHODS OF MAKING AND USING THE SAME INGEVITY UK LTD (GB) 2025-07-17 US claimed
CN-119039557-A Fluorescent water-based polyurethane with anti-counterfeiting function and preparation and application thereof 华南理工大学 2024-11-29 CN claimed
CN-118772398-B Solvent-resistant heat-resistant nylon and preparation method thereof 川化集团有限责任公司 2024-11-19 CN claimed
CN-116459871-B Photocatalyst and preparation method thereof and application of photocatalyst in degradation of phenylsulfone wastewater 南通沃兰化工有限公司 2024-11-05 CN claimed
CN-118772398-A Solvent-resistant heat-resistant nylon and preparation method thereof 川化集团有限责任公司 2024-10-15 CN claimed
WO-2024068129-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE INGEVITY UK LTD. (GB) 2024-04-04 WO claimed
US-20240110002-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE INGEVITY UK LTD (GB) 2024-04-04 US claimed
EP-0716113-A2 Polyamic acid having three-dimensional network molecular structure, polyimide obtained therefrom and process for the preparation thereof Toho Rayon Co., Ltd. (JP) 1996-06-12 EP claimed
WO-1996001862-A1 METHODS FOR THE PREPARATION OF INHERENTLY METAL BINDING POLY-AMINE-QUINONE POLYMERS ERHAN SEMIH (US) 1996-01-25 WO claimed
US-5459233-A High temperature engineering aromatic polyimides MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-10-17 US claimed
US-5443859-A Reacting tetracarboxylic acid dianhydride, aromatic diamine, optionally polyamine, to form polyamic acid, forming film, imidizing to form polyimide, carbonizing in inert gas or vacuum to form carbon film with specifed properties TOHO RAYON CO., LTD. (JP) 1995-08-22 US claimed
US-5288843-A Polymerizing 4,4'-bis(3-aminophenoxy)biphenyl, pyromellitic dianhydride and a different aromaticdiamine; engineering plastics; molding mateials; aerospace; heat resistance; melt processibility MITSUI TOATSU CHEMICALS, INC. (JP) 1994-02-22 US claimed
EP-0202259-B1 SILOXANE-CONTAINING POLYMERS NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1990-07-18 EP claimed
US-4886873-A ELASTICITY AND HEAT RESISTANCE DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1989-12-12 US claimed
EP-0317943-A2 Polymers prepared from 4,4'-bis-[2-(3,4-(dicarboxyphenyl) hexafluoroisopropyl] diphenyl ether dianhydride HOECHST CELANESE CORPORATION (US) 1989-05-31 EP claimed
US-4172937-A REACTION OF A DIALDEHYDE AND DIAMINE IN A PHENOLIC COMPOUND ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1979-10-30 US claimed
US-4107151-A FROM POLYISOCYANATE, CHAIN POLYOL, AROMATIC DIAMINE, POLYOL OR AMINO ALCOHOL WITH URETHANE BOND IHARA CHEMICAL COMPANY CO., LTD. (JP) 1978-08-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015454-A1 HIGH PERFORMANCE, AMBIENT CURE POLYURETHANES COMPRISING POLYCAPROLACTONE POLYOLS PUF60, MORF4L1, C9 MAOA 1471/4885CYP3A4 1622/4885CASP1 307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.