Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16239302 | 0.92 | LMNA (0.38) | LMNAL3MBTL1TSHRMAPTKMT2A | |
| SCHEMBL16237197 | 0.85 | LMNA (0.47) | LMNAL3MBTL1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL16236945 | 0.83 | MAPT (0.47) | LMNAL3MBTL1TSHRMAPTKMT2A | |
| SCHEMBL16236436 | 0.81 | MEN1 (0.42) | LMNAL3MBTL1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL16239305 | 0.79 | KMT2A (0.42) | LMNAL3MBTL1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL16236740 | 0.79 | TNFRSF1A (0.44) | LMNAL3MBTL1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL16236498 | 0.79 | MAPT (0.43) | LMNAL3MBTL1TSHRMAPTKMT2A | |
| SCHEMBL16239354 | 0.78 | ELANE (0.42) | LMNAL3MBTL1TSHRMAPTKMT2A | |
| SCHEMBL16236325 | 0.78 | MAPT (0.42) | LMNAL3MBTL1TSHRMAPTKMT2A | |
| SCHEMBL16555941 | 0.77 | MAPT (0.45) | LMNAL3MBTL1TSHRMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997050-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2016-03-23 | — | — | EP | disclosed |
| WO-2014184171-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2014-11-20 | — | — | WO | disclosed |