SCHEMBL16237197

SCHEMBL16237197

CCN(CC)C(=O)Oc1ccc(C)c(C)c1-c1c(OC(=O)c2ccccc2)ccc(C)c1C

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ TSHR P16473 1/20 0.47
▸ KMT2A Q03164 4/20 0.45
▸ MAPT P10636 3/20 0.45
▸ SMN1; SMN2 Q16637 3/20 0.45
▸ MEN1 O00255 2/20 0.45
▸ NPC1 O15118 1/20 0.45
▸ RAB9A P51151 1/20 0.45
▸ HSD17B10 Q99714 1/20 0.45
▸ SLC6A3 Q01959 1/20 0.43
▸ TSPO P30536 2/20 0.40
▸ POLB P06746 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ PKM P14618 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.39
▸ TOP1 P11387 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16236487 0.88 MEN1 (0.53) LMNAL3MBTL1TSHRKMT2AMAPT
SCHEMBL16236150 0.86 KMT2A (0.52) LMNAL3MBTL1TSHRKMT2AMAPT
SCHEMBL16236627 0.86 HSD17B10 (0.49) LMNAL3MBTL1TSHRKMT2AMAPT
SCHEMBL16237113 0.85 LMNA (0.38) LMNAL3MBTL1TSHRKMT2AMAPT
SCHEMBL16556311 0.83 HSD17B10 (0.57) LMNAL3MBTL1TSHRKMT2AMAPT
SCHEMBL16236449 0.82 LMNA (0.48) LMNAL3MBTL1TSHRKMT2AMAPT
SCHEMBL16236562 0.82 MEN1 (0.47) LMNAL3MBTL1TSHRKMT2AMAPT
SCHEMBL16236713 0.82 KMT2A (0.44) LMNAL3MBTL1KMT2AMAPTSMN1; SMN2
SCHEMBL16236939 0.81 MEN1 (0.46) LMNAL3MBTL1TSHRKMT2AMAPT
SCHEMBL16236870 0.81 LMNA (0.63) LMNAL3MBTL1TSHRKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2997050-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2018-01-17 — — EP disclosed
US-9714303-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2017-07-25 — — US disclosed
US-20160115261-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia, s.r.l. (IT) 2016-04-28 — — US disclosed
EP-2997050-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2016-03-23 — — EP disclosed
WO-2014184171-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2014-11-20 — — WO disclosed
EP-2803678-A1 Catalyst components for the polymerization of olefins Basell Poliolefine Italia S.r.l. (IT) 2014-11-19 — — EP disclosed
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