SCHEMBL16239172

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8807928	0.82	NCEH1 (0.50)	MAPTHTTLMNAPDE4APDE4C
	SCHEMBL30731238	0.82	NCEH1 (0.50)	MAPTHTTLMNAPDE4APDE4C
	SCHEMBL18318687	0.79	PTGS1 (0.38)	ERN1PTGS1PTGS2
	SCHEMBL3609606	0.78	HASPIN (0.56)	HASPINGSK3BDAPK3PLK1PLK3
	SCHEMBL26933457	0.78	HSP90AA1 (0.42)	MAPTLMNAPDE4APDE4CPDE4D
	SCHEMBL24150446	0.76	S1PR4 (0.36)	MAPTHTTLMNAPDE4APDE4C
	SCHEMBL26933718	0.76	HSP90AA1 (0.38)	MAPTHTTLMNAPDE4APDE4C
	SCHEMBL2423484	0.76	KCNA3 (0.48)	HTTLMNAPTGS1PTGS2
	SCHEMBL2312202	0.76	CASP6 (0.38)	MAPTLMNATDP1NCEH1PTPN1
	SCHEMBL18131083	0.75	MAPT (0.42)	MAPTLMNAPDE4APDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.