SCHEMBL16239187

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8671420	0.85	ALDH1A1 (0.52)	HSP90AA1CRHBPCRHR2TSHRNCEH1
	SCHEMBL8609981	0.82	HSP90AA1 (0.49)	HSP90AA1CRHBPCRHR2TSHRNCEH1
	SCHEMBL29908861	0.82	BCHE (0.46)	HSP90AA1CRHBPCRHR2TSHRCA12
	SCHEMBL7484286	0.79	TOP2A (0.52)	HSP90AA1CRHBPCRHR2TSHRNCEH1
	SCHEMBL27972555	0.79	NCEH1 (0.45)	HSP90AA1CRHBPCRHR2TSHRCA12
	SCHEMBL16239118	0.78	CA12 (0.51)	TSHRCA12CA4CA7CA9
	SCHEMBL11889090	0.78	CA12 (0.51)	TSHRCA12CA4CA7CA9
	SCHEMBL17883919	0.77	NCEH1 (0.45)	HSP90AA1CRHBPCRHR2TSHRCA12
	SCHEMBL17819091	0.77	CNR1 (0.52)	HSP90AA1CRHBPCRHR2TSHRNCEH1
	SCHEMBL3655465	0.77	CA12 (0.74)	TSHRCA12CA4CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.