SCHEMBL16239196

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16239091	0.80	P2RX4 (0.59)	P2RX4
	SCHEMBL29908782	0.80	P2RX4 (0.59)	P2RX4
	SCHEMBL16239042	0.79	P2RX4 (0.50)	P2RX4
	SCHEMBL30297208	0.79	P2RX4 (0.50)	P2RX4
	SCHEMBL16239312	0.76	P2RX4 (0.72)	P2RX4
	SCHEMBL15189254	0.76	DRD2 (0.53)	DRD2
	SCHEMBL29908756	0.73	P2RX4 (0.58)	P2RX4
	SCHEMBL16239067	0.73	P2RX4 (0.58)	P2RX4
	SCHEMBL30229634	0.72	DRD3 (0.50)	P2RX4DRD2
	SCHEMBL29908736	0.72	P2RX4 (0.55)	P2RX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.