SCHEMBL16239476

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16239073	0.82	MAPT (0.51)	MEN1KMT2AMAPTRAB9APDE3B
	SCHEMBL28392551	0.79	MAPT (0.47)	MEN1KMT2AMAPTRAB9APDE3B
	SCHEMBL16239200	0.78	MAPT (0.46)	MEN1KMT2AMAPTRAB9APDE3B
	SCHEMBL11553211	0.78	PDE3B (0.52)	MEN1KMT2AMAPTRAB9APDE3B
	SCHEMBL28427593	0.77	MAPT (0.46)	MEN1KMT2AMAPTRAB9APDE3B
	SCHEMBL16239032	0.74	CREBBP (0.44)	MEN1KMT2AMAPTRAB9ASMN1; SMN2
	SCHEMBL7701199	0.74	MEN1 (1.00)	MEN1KMT2AMAPTRAB9AALDH1A1
	SCHEMBL16238949	0.73	P2RX4 (0.64)	MEN1KMT2AMAPTRAB9ATUBB4A
	SCHEMBL30297416	0.73	P2RX4 (0.64)	MEN1KMT2AMAPTRAB9ATUBB4A
	SCHEMBL16239146	0.71	MAPT (0.48)	MEN1KMT2AMAPTRAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.